Week 5 Discussion Group - Case Study #1
A full term female neonate was born to a 21-year-old woman. The baby was found to have icterus at 4 hr. after birth. Upon noticing this, several laboratory tests were ordered.
The patient Patient's blood smear
Normal Blood smear for comparison
Laboratory Test Results:
The neonate’s red cells typed B, Rh+, while the mother’s red cells typed O, Rh=.
A blood smear showed changes typical of hemolysis.
A screen for fetomaternal hemorrhage was negative.
The baby’s G6PD activity was normal.
Sickle cell test had negative results.
An infectious disease evaluation was completed reported as negative.
Day 1 Serum Bilirubin was 10mg/dl. Day 2 Serum Bilirubin was 12 mg/dl Day 3 Serum Bilirubin was 14 mg/dl
Explain fully the following questions:
What is the diagnosis of the neonate’s condition?
What is the treatment for this condition?
What needs to be done for the mother?
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Case Study #2
Clinical history: Over the course of 1 week, a 6-year-old boy develops 0.5- to 1.0-cm pustules on his face. During the next 2 days, some of the pustules break, forming shallow erosions covered by a honey-colored crust. New lesions then form around the crust. The boy's 40-year old uncle develops similar lesions after visiting for 1 week during the child's illness.
Laboratory Findings:
Lesions on patient Growth on blood agar Coagulase test results
Gram stains of exudate from lesions from both patient and patient's uncle.
The Gram stain from a skin pustule are shown above. The organism grew on sheep blood agar (SBA) and was catalase positive. Which of the following organisms do you think is responsible for this pathology?
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CASE STUDY #3
An 2 year-old boy comes to your physician's office with his mother who reports he has redness in both eyes with greenish-yellow discharge x 2 days. When he awakens in the mornings, his left eye is swollen, and he says that it feels like there is "something stuck" in the eye. The mother reports his eyes are both itchy, crusty, and hard to open in the morning. Patient keeps rubbing both eyes and seems uncomfortable while sitting in the exam room. Patient states he has just returned from his day care.
Physical Exam: Reveals an 2 year old boy in good health except for ophthalmic symptoms as noted by the patient. Patient history is unremarkable. Mother states he has no known allergies or chronic illnesses.
Laboratory tests you ordered will take 48 hours to complete - so stay tuned for additional information later.
Week 5 Discussion Group - Case Study #1 A full term female neonate was born to...
A full term female neonate was born to a 21-year-old woman. The baby was found to have icterus at 4 hr. after birth. Upon noticing this, several laboratory tests were ordered. Laboratory Test Results: The neonate’s red cells typed B, Rh+, while the mother’s red cells typed O, Rh=. A blood smear showed changes typical of hemolysis. A screen for fetomaternal hemorrhage was negative. The baby’s G6PD activity was normal. Sickle cell test had negative results. An infectious disease evaluation...
A full term female neonate was born to a 21-year-old woman of Mediterranean descent. The baby was found to have icterus at 4 hr. after birth. Upon noticing this, several laboratory tests were ordered. Laboratory Test Results: The neonate’s red cells typed B, Rh+, while the mother’s red cells typed O, Rh=. A blood smear showed changes typical of hemolysis. A screen for fetomaternal hemorrhage was negative. The baby’s G6PD activity was normal. Sickle cell test had negative...
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A 5-year-old white boy was admitted with a fractured tibia following a playground accident. A CBC was ordered on admission. Parameter Result Reference Range Hemoglobin 10.2 g/dL 11.5-13.5 g/dL Hematocrit 27% 34-41% RBC 3.6 x 1012/L 3.9-5.3 x 1012/L WBC 12.5 x 109/L 4.5-13.5 x 109/L MCV 96.4 fL 75-87 fL MCH 28.3 pg 24-30 pg MCHC 38 % 31-36 % The peripheral blood smear revealed anisocytosis, polychromasia, and numerous RBCs that appeared small and dense when compared to normal...
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