Question

Discuss the following medications: cephalosporins, aminoglycosides, penicillins, tetracyclines, rifampin, INH, acyclovir, Atripla, ritonavir, zidovudine, protease inhibitors, NRTI’s, NNRTI’s, Truvada, AZT, nystatin, amphotericin, fluconazole, clotrimazole

Answer 1

Cephalosporins. It is a large group of antibiotics. Cephalosporins are bactericidal & work in similar way to penicillins. They are called broad-spec- turm antibiotics because they are effective against a wide range of bacteria. Ege Cephalexin, ceftriaxone drugs Aminoglycosides. It is concentration dependent bactericidal activity. These antibiotics bind to the 30s ribosome, there by inhibiting bacterial Protein synthesis 3 Eg drugs - Amikacin, Gentamycin etc. Penicillin & It is common antibiotic, used to treat bacterial infections. It was one of the first to be discovered, he worked well against staphylococci & streptococci. It discovered when I leming noticed a mold that was stoppind bacteria from growing in a petri dish. &gt Penicillin ing etc. Z

Tetracyc It is an antibiotic used to treat a number of infections. That includes ache, cholera , brucellosis, plaque, malariah syphilis. It works by blocking the ability - of bacteria to make proteins. & Minocycline, doxycycline etc -- Rifampicin - It is an antibiotic used to treat several types of bacterial infections including tuberculosis, Musobacterium avium & complex, leprosy & Legionnaires disease a 7 It is recommended & of active tuberculosis. Egi: Rifadin, Rimactane etc- INH; Isonico tin hydrazide it is an antibiotic used for the isoniazid induced neuropathy &gt Isovit

Acyclovir: It is an antiviral drug. It slows the growth e spread of the herpes Virus in the body. It is used to treat infections caused by herpes viruses such -as genital herpes, cold sores, shingles, é chicken Pox, as well as varicella €9: Zoviraxe Atripla: It is antiviral medication that prevent human. (HIV) from repro- ducing in your body. It is used to It is fixed dose combination. tablet containing efavirens, entricitabine e Eg tenofovir. DF - treat WW.

Ritonavir & It is a viral drug. It is used with other Hiv medications to help control HIV infection. A class of drugs belongs to known as protease inhibitors. qg;- Ritonavir Zidovudine & It is an antiviral medicine used to treat HIV, the virus that can cause act, quired immunodeficiency sydrome. It is also given during pregnancy to prevent an HIV infected woman from passing the virus. to her body baby. But this drug not a cure for HIV .

Protease inhibitors ; - It is an antiviral drugs are widely used to Hive Hepatitis con - It prevent viral replication by se lects- -vely binding to vival proteases & blocking- Proteolytic cleavage of protein precursors that are necessary for the production. €9; Ata za navir, Nelfinavir, Darunavir.. NRTI - Nucleoside reverse transcriptase inhibitor. - It does this by using an enzyme called reverse transcriptase. It work bcoz hey block that enzyme - without reverse transcriptase, HIV can't make new virus. copies of itself. &gt zidovudine, lamivudine ete- ne

NNRTI : Non-nucleoside reverse transcrip- tase Inhibitors. - It is bind to ę block HIV reverse transcriptase an HIV enzyme miestol 97 Nevirapine, efavirenz- TRUVADA" It that can help reduce the risk of getting HIV-1 through sex , when taken. everyday & used together with safer sex pra- ctices. - But it doesn't Prevent other sexually transmitted infections. 69 - Emtricitabine & fenofovir disoproxi)

OY AZT & It is antiviral drug. It is azidothymidine It belongs to a group of drugs known as nrl's I - It Prevent HIV. So it is antiretro- viral medicine egi Zidovudine – – – wompo Nystatin. It is an antifungal drug flights infections caused by fungus. Inom It is taken when by mouth is used to treat yeast infections in the mouth & stomach. Oral nystatin is not absorbed into your bild-/ stream & willn't treat fungal infections in other parts of the body or skin. bat & 9; Nystatin ete-

Amphotericin B - It is an antifungal medication used for serious fungal infections such as & G - Fungizone a histoplasmosis Fluconazole. It is used to treat viaginal yeast infections. It works by stopping the growth of common types of vaginal yeast and It is an antifungal drug & Azole antifungals o e l 895 Fluconazole; Diflucan etc Clotrimazole. It is an Azole antifungal. anal cream- - It is used on the skin in & around the vaginal area to reduce symptoms such as burning, itching ę redness that may occar with a vaginal yeast infection? 89- Clotrimazole & luconazole nos yul