Question

The physician orders a lab technician to perform a Kirby Bauer disk diffusion assay and finds that the organism is resistant to the following antibiotics: 1) Penicillin, 2) Ampicillin, 3) Methicillin, and 4) Trimethoprim/Sulfamethoxazole. The physician asks the man about any drug allergies and other pre-disposing factors that could impact anti-microbial therapy. The man is allergic to all of the beta-lactam antibiotics, all cephalosporins, and does not tolerate sulfa drugs well. The man also has a form of hepatitis from a botched blood transfusion several years prior. 1.3 Based upon this recent revelation, what drug would you choose to treat the patient with? (2 points) Why did you choose that drug? (3 points) 1.4 After two weeks of antibiotic treatment, the mass has not retreated, and is now very hard. What would be the next logical course of action? ß points)

Answer 1

1.3 Aminoglycosides included amikacin (amikin) , gentamicin , kanamycin ( kartex) neomycin , streptomycin and tobramycin.

Aminoglycosides Actions :-

the aminglycoside exert their bactericidal effect by blockin a step in protein synthesis necessary fro bacterial multiplication they disrup the funtional ability of the bacterial cell wall , causing death.

Aminoglycosides Uses :-

Narrow-specturm antibiotics that are useful for the treatment of serious gram-negative infections, , When treating a bacterial infection in a patient with hepatic failure, this drug class could be used