Ans.1.63%
Bioavailability is the fraction of administered drug that reaches the systemic circulation .
Bioavailability is expressed as the fraction of administered drug that gain access to the systemic circulation in a chemically unchanged form.
The bioavailability of a drug administered by a given route is determined by the total amount...
You want to achieve a particular plasma concentration of a drug of approximately 81 mg/L in a 70 kg adult male. You know that the total volume of distribution for this drug is ~9L. What dose of drug should you give? (Choose the closest approximate value.) 5670 mg 729 mg correct 10 mg 9 mg In order to achieve the same plasma concentration of the above drug in an adult male who is obese (weighing 125 kg) but otherwise healthy,...
Using the example on the first sheet, figure out how much drug
at each dose (second sheet) for administration bid( twice daily)for
3 days to mice.
The Free base of the drug is 91.62% and the vial =16 ml.
Calculation of Drug at 5 Doses for Administration bid for 3 Days to Mice Example method for Drug 1 (95% free base) to be mixed once to be administered via any route bid for 3 days to mice. Dose levels 64,32,16,8,4&...