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According to various surveys conducted in the US, over 50% of pregnant women take at least one medication during their pregna

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In this case the clearance of the drug will be increased, as the elimination rate will be increased of the antidepressant drug as it is metabolized by the liver enzyme CYP2D6.

as Elimination rate = clearance X plasma drug concentration.

And if elimination rate will increase, then the clearance will also increase .

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