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A 78-year-old woman comes to the clinic for a new-patient examination. She reports that she smokes Cannabis several...

A 78-year-old woman comes to the clinic for a new-patient examination. She reports that she smokes Cannabis several times a week and also takes alprazolam 0.5 mg three times per day, a combination tablet of metoprolol tartrate 50 mg/hydrochlorothiazide 25 mg daily, aspirin 81 mg daily; garlic soft-gels 1000 mg twice a day; and ibuprofen 400 mg four times a day.


1. Do any of these drugs appear on the 2015 American Geriatrics Society Beers Criteria for Potentially Inappropriate Medication Use in Older Adults? If so, what do the criteria say about them?


2. What interactions exist among the drugs

and supplements this patient is taking?


3. What is the evidence for taking garlic to reduce cholesterol?


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1 :- The American Geriatrics Society Beers Criteria for Potentially Inappropriate Medication use in Older Adults are widely used by clinicians , educators, researchers , healthcare administrators and regulators. AGS produces updates in every three years, it's Beers Criteria is an open list of PIMs avoided by older adults under specific situations, such as in certain disease conditions. Since the last update in 2015 to determine if new Criteria should be added or if existing should undergo change to their recommendations , rationale, level of evidence, or strength of recommendation.

The 2015 AGS Beers Criteria are applicable to all older adults with the left out of those in palliative and hospice care,. Careful application of the criteria by health professionals, consumers, pastors and health systems should lead to closer monitoring of drug use in older adults.

2 :- The 78 years old woman reports show that a drug interaction is a situation in which a subtances affects the activity of a drug.that may be increased or decreased,or produce new effects or not any . Therefore , by using such drugs , smoke ,garlic hell , that produces a medical challenge that is not just to avoid interactions . Instead the physicians faces the question of how to proceed with drug treatment in the presence of such interactions. Based on medical education the physician has to Jude all to avoid any risk factor , then prescibepra prescription so that the patient could feel relief if the resistance of the prescribed drug surpass already resisted drugs and smoke that the patient is taking.

3 :- Garlic contains the chemical allicin, that kills bacteria band fungi and alleviate digestive disorders. But the most notable attention is that garlic lowers cholesterol , being a herbal supplement about one gram of garlic is sufficient for a day, in whatever form help to lower cholesterol.

In ancient times garlic was used to treat deafness , dropsy , intestinal parasites , leprosy, respiratory illness and loss of appetite. Today it's used as a food seasoning that help multiple ailments , including cholesterol decrease9 to 12 % that is the more garlic you take , the lower your cholesterol will drop.

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