Question

What is the product of the following reaction?

CH30Nat CH3OH 00H OCH OCH;

Answer 1

This is a nucleophilic aromatic substitution reaction.
CH3 Or Nat Tietot NO Aromatic (2.g. Noprefer Electron With drawing group substitution at ortho and para nucleophisia positions A typical nucleophilic substitution has or. Cyanide nucleophile . An . Oxygen, Nitrogen A halide for leaving group or cyanide group - A carbonyl, nitro ortho and/or ( Electron with drawing group) para to the leaving group. reaction is so, the above Nucleophilic. Aromatic substitution Cho es is is Nucleophile, reaction, Dhere and NO2 la electron Withdra- leaving group para position. wing group)' at Hence, the mechanism shown below

CI OCHS CI Octs | Caso wat 1 ] Wat = - - 0 NA Nucleophilic «tr ску. CABOT. This intermediate is stabline by and besonance also by EWG NO2: | 0 Locks Clocks Hoteller COLH3 - HOCHS OCHS tcr nat ei is a good leaving group, so it leaven. 6cts [1 Hence, in tenses the product in- the product NO