2. The figure below shows two possible methods for the production of acetyl CoA from acetate as part of the biosynthesis of fatty acids in the body. The first method is a direct reaction, and the second method involves coupled reactions.
Direct Reaction
Coupled Reactions
Step 1
Step 2
a. The standard Gibbs free energy for the direct reaction, ΔG°', is 32 kJ/mol. (Note that the prime symbol is used for biological systems.) Calculate the equilibrium constant for the reaction at a temperature of 298 K. Is the reaction favorable or unfavorable? Explain. (1 point)
b. Calculate the equilibrium constant for each step of the coupled reactions. ΔG1°' is about 11 kJ/mol for the first reaction, and ΔG2°' is about –10 kJ/mol for the second reaction. Is each step favorable or unfavorable? Explain. (1 point)
c. Determine the net reaction for the coupled reaction, its Gibbs free energy value, and its overall equilibrium constant. (1 point)
d. Predict whether the direct method or the coupled reaction method would be more likely to occur in the body to produce acetyl CoA from acetate. What might happen to make the reaction even more likely to occur? (1 point)
----------
For a) I got K = 0.00000258 or 2.58 * 10-6
For b) I got
K1 = exp[ (-11000J mol-) / (8.314 J K-1 mol-1)(298.15 K)] = 0.01182
K2 = exp[ -(-10000J mol-) / ((8.314 J K-1 mol-1)(298.15 K)] = 56.4965
ΔG1o is unfavourable as it is greater than 0
ΔG2o is favorable as it is less than 0
I can't figure out C and D at all.
2. The figure below shows two possible methods for the production of acetyl CoA from acetate...
3. (10 pts) Citrate synthase catalyzes the reaction: Oxaloacetate + acetyl – COA → citrate + HS – COA The standard free energy change for the reation is -31.5 k] . mol-1. a) Calculate the equilibrium constant for this reaction at 37°C. b) Would you expect this reaction to serve as a control point for its pathway (the citric acid cycle)?
36.(a) Choose all of the statements from below which correctly describe issues pertaining to the relationship between the emf of a reaction and its Gibbs free energy change. The Gibbs free energy change and emf values of a reaction have opposite algebraic signs (+ vs. -). A Gibbs free energy change involves moles of substances whereas an emf involves coulombs of electrons. Electron stoichiometry must be used to interconvert a Gibbs free energy change and a reaction emf. A coulomb...
Please help answer ALL the following questions in the attachment. Please answer only if you’re certain. Thank you so much for your help. 1 Find the mismatched pai a) Entropy (AS-measurement of disorder in a thermodynamic system b) AG<0-Energetically favorable (spontaneous) reaction c) First Law of Thermodynamics-Energy in a system is not created nor destroyed, only transformed d) Second Law of Thermodynamics-The entropy of a perfect crystal at 0 K is exactly equal to zero. e) Standard free energy (G-The...
41. Find the mismatched pair: A) Entropy (ΔS)—measurement of disorder in a thermodynamic system B) First Law of Thermodynamics—Energy in a system is not created nor destroyed, only transformed C) Second Law of Thermodynamics—The entropy of a perfect crystal at 0 K is exactly equal to zero. D) Standard free energy (Go )—The useful energy in a system E) ΔG < 0—Energetically favorable (spontaneous) reaction 42. Which of the following reactions is unfavorable? A) NaCl dissolving in water (ΔG <...
21C.1(a) The reaction of propylxanthate ion in acetic acid buffer solutions has the mechanism A− +H+→P. Near 30 °C the rate constant is given by the empirical expression kr=(2.05×1013) e−(8681K)/T dm3mol−1 s−1. Evaluate the energy and entropy of activation at 30 °C. 21C.1(b) The reaction A− +H+→P has a rate constant given by the empirical expression kr=(6.92×1012)e−(5925K)/T dm3mol−1 s−1. Evaluate the energy and entropy of activation at 25 °C. Please explain why they calculated H=E-RT like that like why is...
Please I need help on this. I'm so lost 1. Acetic acid (H)CO2H) has k, = 1.8 x 10- and acetate (H:C:01") has ks = 5.6 x 10-10. (a) Write balanced chemical equilibrium equations (with physical states) for acid dissociation of acetic acid and base hydrolysis of acetate ion. (b) Write K, and equilibrium constant expressions for the above reactions. (c) Use your expressions from part b to show that Kx. = 1.0 x 10-* = [H,O'][OH). 2. For each...
please help answer question 4, a-f please using the data below from chart 1 objectives from lab, thank you DATA:CA y 3 Ay No3 Part I: Cell Potential of voltaic cells under standard conditions: cell CU CND2 #27 14.0m Give the half Half cell reaction at Combinations Oxidation Reduction E the anode and with [ion] takes place Theoretical takes place cathode. Write in M here here (V) above the arrow E c (V) if it is oxidation or reduction. |-0.340...