Question

1. Propose synthesis for the following transformations, they should all require multiple steps: он 2. он

Answer 1

1(a) Ö: OH H2 soy,H 0: OH 0 It) n the above process ,firstly ure oxidized alcohof witth R2C 07, H H20 . and fotrna ketone. Now, use anignand Meagent in he t res ence of acid,メo reduce ketone- natde reducing agent 0

:Bx. OH 9, ether HO) mechanism : By OH OH ether O: 0H Oh HO OH 8) NaCN, H20 OH

Mechanism: BY: 古n) (mono bromineior) E2 NaoEt m-CPBA O: acN SN 2 outtack CN e m-C PBA oxidieing at it i uted eboxidation of alkene

4) 2) : CP ·Initiation : Ph Benzo Propagation BY: (ac chloride) Benzo ye ben oxid wort、gas atladicop initiator here.