There is tyrosine protease, which uses similar mechanism to cysteine protease. write down the mechanism
There is tyrosine protease, which uses similar mechanism to cysteine protease. write down the mechanism
iAt p6, carbonic anhydrase has a keue of 60,000s'. please estimate the ku, if the phf is 13 increased to 7.0. Please justify your answer. Co,+ H20H2CO 14. The two person have the same k after drinking alcohol. Please calculate the substrate earbonie enhydrase concentration in Person 1. Please justify your answer. Person 1 Aldehyde koolS') Km (M) erson 2 dehydrogenase 0.0002 0.006 0.002 15. There is a tyrosine protease, which uses similar mechanism to a cysteine protease. Write down...
The HIV protease enzyme uses a general acid-base catalysis mechanism to cleave viral polypeptides but does not use a covalent catalysis. This enzyme functions optimally in the pH range of 4-6. Due to the specific amino acids involved in this catalysis, HIV protease is a member of which subclass of proteases? Select one: A. metalloproteases B. aspartyl proteases C. serine proteases D. lysine proteases E. cysteine proteases
Papain is a cysteine protese from the papaya plant. It is commonly used for breaking down protein deposits that build up on contact lenses. Instead of having a catalytic triad like in serine protease and hydrolyases, it has a catalytic dyad comprised of cysteine and a histidine with an asparagine assisting in catalysis. a) Propose a mechanism for the hydrolysis of a peptide by pepain. b) Why is cysteine more nucleophilic than serine? c) Why might C1 be even more...
Treatment the hexameric peptide, EMGNKC, with AspN-protease yields which of the following products:Note that Asp-N protease hydrolyzes peptide bonds on the N-terminal side of the amino acids: aspartic acid and cysteine. this is the answer EMGNK andC
7. The HIV protease structure was solved very early in the process of developing anti-HIV drugs. Importantly, the protease was found to be quite similar to proteases like chymotrypsin and trypsin. Compare and contrast the catalytic mechanism and binding properties of chymotrypsin, trypsin, and the HIV protease. Catalitic mechanism chymotryps in this enzyme help digest and works in the intestine to help Break down Large protein molecules
The thiol group (R-SH, found in the amino acid cysteine) is very nucleophilic even when it is not deprotonated. With that information, write down a detailed mechanism (using curved arrows to indicate the movement of electrons) and the product of the intramolecular reaction below. Also please designate all stereocenters as R or S in the starting material and product(s).
9.61 (•-..) Suggest a mechanism for the following reactions which are similar to the mechanism we saw for lanosterol biosynthesis at the end of Chapter 8. (a) LOCH3 (b) V Br und 90.com, wabung H2SO4, CH3OH Bunting when s5 HO H-Br In addition to the End of Chapter problems in this book Sections
How many tetrahedral intermediates occur during the serine protease mechanism. Which of the following is not a general property of most enzymes. Answer by placing the number in the box. There is only one correct answer. 1. The active site takes up a small portion of the enzyme's surface. 2. The enzyme binds to the substrate via a few strong interactions. 3. Amino acids that make up the active site can be far apart in the primary sequence. Which of...
7. Write down the Chapman mechanism and explain why it predicts a layer of ozone in the stratosphere. Why is the ozone concentration that is predicted by this mechanism significantly more than is observed from measurements?
Write down a detail step by step mechanism for the reaction of primary alkyl halide with NaI/Acetone. please show all the steps and write neat. thank you!