5. Another patient has a family history in which: 1. males and females were equally affected...
5. Another patient has a family history in which:
1. males and females were equally affected
2. two of the offspring from two unaffected parents
were affected, while the other six offspring were
unaffected.
What type of inheritance is this likely to be?
A. Autosomal dominant
B. Autosomal recessive
C. X-linked dominant
D. X-linked recessive
Homework Answers
males and females were equally affected
here both males and females are affected so this disease is autosomal.
two of the offspring from two unaffected parents were affected, while the other six offspring were unaffected.
normal parents have affected progenies this shows the disease is recessive and the parents were heterozygous
let the alleles be D-normal dominant d-recessive
| D | d | |
| D | DD ( normal) | Dd ( normal) |
| d | Dd ( normal) | dd ( affected) |
normal:affected=3:1
so the disease is B) Autosomal recessive
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