Question

February 19 before the start of lss Concise, short answers only. Long drawn out answers will not be graded even if they contain the correct answer. (True or False) GPCRs for dopamine tend to be located directly across from the release site 1. 2. If you knock down the activity of dopa decarboxylase in a dopaminergic neuron, this neuron would have increased levels of what intermediate? 3. What molecule will associate with α1 noradrenergic receptors if they are bound to norepinephrine for too long? 4. The mesolimbic pathway arising from the ventral tegmental area (VTA) is involved in what sensation? 5. Activation of the D1 dopamine receptor has what affect on DARPP-32? 6. Degeneration of the nigrostriatal system would lead to loss of synaptic terminals in what general brain area?

Answer 1

Ans 1-true.

Ans2- levodopa (L-dopa).

Ans 3- Ca+2 by Ip3 pathway associated due to long turm binding of norepinephrine wth alpha noradrnergic receptor.

Ans 4- olfactory.

Ans 5-It will leads to phosphorylation.

Ans 6- substantia nigra located in mid brain.