Question

Many biochemical reactions are catalyzed by acids. A typical mechanism consistent with experimental result (in which HA is the acid and X is the reaction) is

stepl : Fast, reversible : HA + H+ + A-

step 2: Fast, reversible: X + H^{+}\leftrightarrow XH^{+}

step 3: Slow: XH^{+}\rightarrow products

What is the rate law that is consistent with the proposed mechanism?

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Answer #1

Among all the three steps,

step3 is the slowest step, since the rate of the reaction depends on the slowest step, the rate law can be written as

r = k [XH+]

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