Question

43 Exp 6: Liquid-Liquid Extraction Week 2 Objective The purpose of this experiment is to apply what you've leaned about liquid/liquid separations to the analysis of a simulated mixture of Methylenedioxypyrovalerone (MDPV, aka 'Bath Salts') and an unknown cutting agent. Your goal is to separate the cutting agent from the drug. You will also need to test the compound purities. Acid/base extraction is one of the more difficult principles in organic chemistry to understand. The most straight-forward approach to understanding this subject is to create a flow chart (mentally or on paper) to follow which species has been created and where the molecule resides. If you can imagine the molecule changing and moving to the appropriate layer, you will be able to complete the unknown separation very easily o Cr MDPV DHICI salt) Figure 1: Chemical structure of MDPV and its HCl salt The cutting agent is either Acetylsalicylic Acid or Benzophenone. You will be assigned your mixture once the prelab is completed. It is up to you to design the experiment but you should consider the procedures given in extraction 1 and extraction 2 labs. Chemicals and supplies: The drug mixture, hexane, 1M NaOH(aq), 1M HCl(aq), DI water, MgSO, and filter paper. Standard lab equipment. Prelab questions Draw the structures of Acetylsalicylic Acid and Benzophenone Using some or all of the materials available propose a method to separate the Acetylsalicylic Acid from MDPV. Draw a flow chart. Hint think about the pKa of carboxylic acids. Using some or all of the materials available propose a method to separate the Benzophenone from MDPV. Draw a flow chart 1. 2. 3. 4. What methods will be employed to test the identities and purities of the compounds?

Answer 1