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Required information 2. Lisa was moderately overweight, and the physician recommended that she lose weight to help alleviate
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Ans. 2 decreases insulin resistance

There is direct coorelaion between the size of adipocytes of an individual and the insulin resistance which is directly proportional to each other . Thus decreasing the amount of adipose tissue/ decreasing the size of the adipocytes will lead to decrease in the insulin resistance.

Ans.3 slight insulin resistance can cause glucose to enter the urine following a meal when the glucose levels are excessively high

Normally , following a meal there is enough insulin release to compensate for the hyperglycemia but if there is slight insulin resistance , the amount of insulin released is not enough to compensate for the hyperglycemia resulting in excessive glucose getting filtered through the glomeruli following a meal , and if the concentration of the glucose filtered exceeds the renal threshold, it will lead to glycosuria ( occasional glycosuria after meal)

Ans.4 glucose in the kidney tubules decrease the reabsorption of water in the renal tubules

Elevated blood glucose levels ( hyperglycemia) results in excessive glucose getting filtered through the glomeruli . This excess glucose causes osmotic diuresis ( i.e excess of glucose in the tubules cause retention of water inside the tubules due to their high osmolarity) resulting in polyuria .

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