Question

In cancer biology, it is important to understand the difference in types of cell growth in order to properly diagnose and treat cancers. With tumors, what are the similarities and differences between a benign tumor and a malignant tumor?  

Answer 1

Ans- The benign tumor are mass of cells(tumors) that lacks the ability to metastasize i.e. they cannot invade the neighbouring tissues. Although they do not spread, but can be quite large.

The malignant tumors or cancer is a group of diseases involving abnormal or uncontrolled cell growth with the potential to spread or invade other parts of the body.

Similarities and dissimilarities between the two are:

Similarity All tumors, benign and malignant, have two basic components: 1. Clonal neoplastic cells that constitute their parenchyma Reactive stroma made up of connective tissue, blood vessels, and variable numbers of macrophages and lymphocytes 1.

Benign Tumors Malignant Tumors Cell characteristics (well differentiatec) Similar to cell of origin Dissimilar from cell of origin (poorly dfferentiatec) Growth characteristics outward in a smooth move outward in an Tumor edges move The tumor edges manner (encapsulatec), irregular fashion grows by expansion (usuaily no capsule) and compresses and and can infiltrate displaces surrounding invade, and destroy tissues surrounding tissues Tumor cells stay attached to the clone away from the cloned or mass of cells and mass, live do not break away and start new growths to other area of the elsewhere in the bodybody and start new Tumor cells can break independently, move clones or growths Rapid growth rate Moderate-marked Rate of growth Slow growth rate Degree of vascularity Slight vascularity vascularity Recurrence after surgical removal Seldom recurs after Frequently recurs removal after removal Degree of necrosis and ulceration Necrosis and ulceration unusual Necrosis and ulceration common Likelihood ofSystemic effects are Systemic effects are causing systemic effects tumor is a secreting life-threatening unusual unless the common and usually endocrine neoplasm