Question

21. Starting with isopropyl alcohol as the only organic material, synthesize isopropyl propyl ether. Show mechanism. CH3 Section: 10-4 снасH2CH2ОснсH3

Answer 1

21. starting with isopropyl alcohol as the only bot organic materials, synthesize isopropyl oi ab propyl ether, show mechanismen 2008 OH Mount H3C - CH che El Hout Isopropyl alcohol to Igorgoor wat its only yong do? Hugo H3C - CH - CH3 H3C- CH2-CH2-O-CHI TcH3 Isopropyl propyl alcohol Mechanism - HO 애 H2SO4 OH H3C - CH - CH H3C - CH - CH2 1042 H3 C CH - H3C - CH = CH2 1-propene. Hъс си осно BRR RRBH/ THE H3C - CH H2O2 jou H2O H3 C- CH2 - CHO OH -CH propanol

H3C- CH2 - CH2-OH PBrz Base H3C - CH2 - CH2 - Br. 1- Bromopropane. Hъс си - H3 Ман H3C H/CH3 bu Isopropyl alkosice ion H3C H2CH3 CH2 HC Hg CH-O-CH2-CH2-CH3 нас" first isopropyl alcohol can be converted to 1-Bromopropane. Bromide ion is good Leaving group Isopropyl alcohol can in strong acidic condition it converts to I-propene. Hydroboro Hydroboration reaction on 1- propene formation of i-Propanol. In - Propano oh group is not good Leaving group therefore it convert to good Leaving group by and PBrz we get -1- Bromopropane. In which Br is good bearing group.

Meanwhile Base NaH it acts as some isopropyl alcohol treated with to form an isopropyl alkoze'de ion nucleophile. When isopropyl alkozide ion treated with 1-Bromo propune to form to isopropyl propyl ether. o Another method. 1 H H3CH CH3 H2SO4 H₂C - HT CH2 not H2SM > HO HBC CH2 Broash Her M202, 2007 H3C-CH=CH2 EN inn HO-OH 204 OH HO +H. for Br +420 Hะ 12 8 3 2 chaty ce Tot B4 Halt 43c - CH 143 H3C - CH CH3 2 E13 o Hze et CH2 CHA 14 H3CH -0-CH2 CH2 CH2