Mutations in the CFTR gene result in cystic fibrosis in humans, a condition in which abnormal secretions are present in the lungs, pancreas, and sweat glands. In the effort to positionally clone the CFTR gene, the gene was mapped to a region of 500 kb on chromosome 7 containing three candidate genes. Using your knowledge of the disease symptoms, how would you distinguish between the candidate genes to decide which is most likely to encode the CFTR gene?
A.
CFTR gene is expressed in
i. sectreted by epithelial cell
ii. acts as secretory protein
iii. acts as transmembrane protein
Mutations in the CFTR gene result in cystic fibrosis in humans, a condition in which abnormal...
How can you prove that your chosen candidate is the CFTR gene? Select the three correct answers. Problem 16.15 Mutations in the CFTR gene result in cystic fibrosis in humans, a condition in which abnormal secretions are present in the lungs, pancreas, and sweat glands. In the effort to positionally clone the CFTR gene, the gene was mapped to a region of 500 kb on chromosome 7 containing three candidate genes. Part A Using your knowledge of the disease symptoms,...
3. Cystic fibrosis (CF) is an autosomal recessive disorder (cc) and is one of the most common life-shortening genetic diseases. In the United States, 1 in 4,000 children are born with CF. Symptoms of cystic fibrous include the production of salty sweat and thickened mucus in the lining of the lungs and air passages. The thickened mucus obstructs airways and promotes the growth of disease-causing bacteria in the lungs. Most individuals with cystic fibrous die in their 20s and 30s...
please help with Q. 9, 22, 59, 72. thanks! Bookmarks People Tab Window Fra * Q Genetica Fral *1 ses/213459/quizzes/255809/take Help What are the typ * Q Fram Stud Pashcards - Be * Q D Question 9 1 pts Which of the following in determining the phenotype for the ABO blood system is correct? A. Ois dominant over A Ais dominant over B O is recessive Bis dominant over A D Question 10 1 pts Two phenotypically normal individuals have...
2. A dominant allele H reduces the number of body bristles that Drosophila flies have, giving rise to a “hairless” phenotype. In the homozygous condition, H is lethal. An independently assorting dominant allele S has no effect on bristle number except in the presence of H, in which case a single dose of S suppresses the hairless phenotype, thus restoring the "hairy" phenotype. However, S also is lethal in the homozygous (S/S) condition. What ratio of hairy to hairless flies...