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5. Which of the following statements concerning the Bohr effect are true. A. Lowering the pH shifts the oxygen dissociation curve for hemoglobin to the right B. The acidic environment of an exercising muscle allows hemoglobin to bind O2 more tightly C. The affinity of hemoglobin for O2 is diminished by high concentrations of CO2 D. In the lungs, the presence of higher concentrations of H and CO2 allows hemoglobin to become oxygenated E. In the lung, the presence of higher concentrations of O2 promotes the release of CO2 and H from hemoglobin molecules

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Carbon dioxide reacts with water to form carbonic acid, an increase in CO2 results in a decrease in blood pH, resulting in haemoglobin proteins releasing their load of oxygen. Conversely, a decrease in carbon dioxide provokes an increase in pH, which results in haemoglobin picking up more oxygen. so answer is C. The afinity of hemoglobin for O2 is diminished by the high concentration of CO2 and A. is the asnwer as the curve is sigmoidal but yes after experimentation it was clear that the curve shift towards right on lowering pH .

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