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Date Submitted Deadline: November 26, 2018 1. Refer to the structure of a fatty acid below (A) What is the systematic name of this fatty acid? (B) What is the common name of this fatty acid? (C) What is the shorthand notation of this fatty acid? (D) Is this an W-3 or w-6 fatty acid? (E) What would be its melting point relative to linoleic acid? (F) What would be the general effect of this fatty acid in the fluidity of a biological membrane? 2. Phosphatidylcholine (PC) is a glycerophospholipid and a major component of biological membranes and can be easily obtained from a variety of readily available sources, such as egg yolk or soybeans. This phospholipid is composed ofa choline head group and glycerophosphoric acid, where the first two carbon of the glycerol backbone are each esterified to a fatty acid. One of the fatty acid is usually a saturated fatty acid and the other is an unsaturated fatty acid (A) IlIlustrate the Fischer projection of 1-stearoyl-2-linoleoyl-3- phosphatidylcholine (B) PC is more commonly found in the exoplasmic or outer leaflet of a cell membrane. How would PC be oriented in a lipid bilayer? Illustrate schematically and discuss your answer briefly 3. How is cholesterol oriented in biological membranes? You may support your answer with a schematic illustration How does the cholesterol affect the mechanical stability lipid order, and fluidity of biological membranes?
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