Question

Craig has one short copy and one long copy of the serotonin transporter gene. What does this tell us about his vulnerability for major depressive disorder? Craig has a moderate chance of developing major depressive disorder, but this is more likely if he is exposed to severe stress. It is completely certain that Craig WILL be diagnosed with major depressive disorder at some point during his lifetime. It is completely certain that Craig will NOT be diagnosed with major depressive disorder. Craig has a moderate chance of developing major depressive disorder, regardless of his lifestyle and exposure to stress.

Answer 1

1) The answer is - (a) Craig has a moderate chance of developing a major depressive disorder, but this is more likely if he is exposed to severe stress.

Explanation - Serotonin transporter gene is involved in the reuptake of serotonin. It has two versions of alleles, a long one and a short one. It can lead to genetic vulnerability and a stressful environment can result in depression. Those with short alleles are more likely to become depressed when they are exposed to multiple stressful life events. It increases the risk of depression. The combination of both creates a moderate chance of depressive disorder.

2) The answer is - (b) lower concentration of serotonin in the brain and CSF

Explanation - Low serotonin levels in psychiatric patients increases the risk of suicide. It also causes anxiety, sleeping disorders, and depression.

HEY! THUMBS UP AS IT MOTIVATES US.