Homework Answers
The expression is not going to be different in both cases. In both cases, a heterozygous female would be a carrier of Funitis.
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Qcode Bio 200 3-1 Funitis is a recessive genetic condition caused by a mutation in the...
Hemophilia A is a genetic disorder of recessive X chromosome mutation of the Factor VIII gene...
Hemophilia A is a genetic disorder of recessive X chromosome mutation of the Factor VIII gene that causes a blood clotting protein Factor VIII missing or deficient. If a person with XY chromosomes is affected by Hemophilia A and a person with XX chromosomes is an unaffected person, what is the probability that their male offspring might be hemophilic and what is the probability that their female offspring might be carriers of the mutated gene?
1) What is the molecular basis of dominant and recessive alleles (for complete dominance; ignore incomplete...
1) What is the molecular basis of dominant and recessive alleles (for complete dominance; ignore incomplete dominance, epistasis, etc.)? To answer this question, consider the following: a) If alleles are copies of the same gene, why are two types of alleles? What differentiates a dominant allele from a recessive allele (at the molecular level)? Be specific (base pairs, transcription/translation method, protein produced, etc.) b) Why is the phenotype determined by the dominant allele in heterozygous genotype? Be specific. c) What...
3. Sickle-cell disease is a genetic condition caused by an autosomal recessive allele which al- fects...
3. Sickle-cell disease is a genetic condition caused by an autosomal recessive allele which al- fects one in every 500 African American children born in the U.S. One in every ten African Americans is a carrier for the recessive allels. Although sickle cell disease is caused by a single human gene, it is expressed through many different effects throughout the body. The presence of a recessive sickle-cell allele in humans causes the red blood cells to produce abnormal hemoglobin protein...
4) Cystic fibrosis is a human disease caused by an autosomal recessive mutation. About 1 in...
4) Cystic fibrosis is a human disease caused by an autosomal recessive mutation. About 1 in 22 people in the human population are heterozygous carriers and have no symptoms of the disease. A woman who has a brother with CF marries a man who has no history of CF in his family a) What are the possible genotypes of the woman? b) What is the most likely genotype of the man? c) What is the percentage of offspring that would...
2. Color Blindness with a Twist: As a genetic counselor, you may face some ethical dilemmas....
2. Color Blindness with a Twist: As a genetic counselor, you may face some ethical dilemmas. Imagine that a couple came to your office to discuss potential color blindness in their children. The man is not color blind, but his wife is. They already have one daughter that is color blind and want to know the probability of future children having the disorder. First, you will need to explain to the couple the difference between sex chromosomes and autosomal chromosomes...
1. Animals can teach us genetics. Match Codominance Show a dominant and recessive relationship _An allelic...
1. Animals can teach us genetics. Match Codominance Show a dominant and recessive relationship _An allelic series A dominant homozygote is lethal Coat coloration is determined by 2 genes Shows variable expressivity A qualitative, or continuous, trait involving polygenes Females mosaics for X-linked heterozygous color genes A. Manx cat B. Coat coloration rabbits C. Labrador retriever dogs D. Piebald spotting in beagles E. A and B blood alleles F. A and O blood alleles G. Calico cat H. Height of...
5. (2pts) a-thalassemia is a human genetic condition resulting in severe anemia because blood cells can...
5. (2pts) a-thalassemia is a human genetic condition resulting in severe anemia because blood cells can not efficiently carry oxygen to body tissues. a- thalassemia occurs when the HBA1 gene is mutant such that no protein product is made or a non-functional protein is produced. Recently, microRNAs have been implicated in regulating expression of the HBA1 gene. Below is microarray data showing the amount of expression of different microRNAs where each row corresponds to the different miRNA indicated on the...
5. (2pts) a-thalassemia is a human genetic condition resulting in severe anemia because blood cells can...
5. (2pts) a-thalassemia is a human genetic condition resulting in severe anemia because blood cells can not efficiently carry oxygen to body tissues. a-thalassemia occurs when the HBA1 gene is mutant such that no protein product is made or a non- functional protein is produced. Recently, microRNAs have been implicated in regulating expression of the HBA1 gene. Below is microarray data showing the amount of expression of different microRNAs where each row corresponds to the different miRNA indicated on the...
Genetics Worksheet Week 3: Gene Regulation and Epigenetics 1. Duchenne muscular dystrophy is caused by a mutation in a gene that is 2.5 million nucleotides in length and encodes a protein called dyst...
Genetics Worksheet Week 3: Gene Regulation and Epigenetics 1. Duchenne muscular dystrophy is caused by a mutation in a gene that is 2.5 million nucleotides in length and encodes a protein called dystrophin. The dystrophin protein itself is 3684 amino acids in length. Calculate below the approximate size of the mRNA that encodes dystrophin. Approximately what percentage of the gene that encodes dystrophin is intron sequence? The human genome encodes a much greater variety and number of proteins than the...
1. Describe two kinds of recombination in eukaryotes. True of False 2._____ A recessive phenotype can...
1. Describe two kinds of recombination in eukaryotes. True of False 2._____ A recessive phenotype can be expressed by some progeny of a monohybrid cross. 3._____ Epistatic genes may result from dominant or recessive alleles. 4._____ At a single locus, a diploid individual may have more than two different alleles. 5. _____ A temperature-sensitive allele is an example of a genotype x environment interaction. 6. _____ All of the genetic material in a eukaryotic cell is found in the nucleus....
3. Sickle-cell disease is a genetic condition caused by an autosomal recessive allele which al- fects one in every 500 African American children born in the U.S. One in every ten African Americans is a carrier for the recessive allels. Although sickle cell disease is caused by a single human gene, it is expressed through many different effects throughout the body. The presence of a recessive sickle-cell allele in humans causes the red blood cells to produce abnormal hemoglobin protein...
2. Color Blindness with a Twist: As a genetic counselor, you may face some ethical dilemmas. Imagine that a couple came to your office to discuss potential color blindness in their children. The man is not color blind, but his wife is. They already have one daughter that is color blind and want to know the probability of future children having the disorder. First, you will need to explain to the couple the difference between sex chromosomes and autosomal chromosomes...
1. Animals can teach us genetics. Match Codominance Show a dominant and recessive relationship _An allelic series A dominant homozygote is lethal Coat coloration is determined by 2 genes Shows variable expressivity A qualitative, or continuous, trait involving polygenes Females mosaics for X-linked heterozygous color genes A. Manx cat B. Coat coloration rabbits C. Labrador retriever dogs D. Piebald spotting in beagles E. A and B blood alleles F. A and O blood alleles G. Calico cat H. Height of...
5. (2pts) a-thalassemia is a human genetic condition resulting in severe anemia because blood cells can not efficiently carry oxygen to body tissues. a- thalassemia occurs when the HBA1 gene is mutant such that no protein product is made or a non-functional protein is produced. Recently, microRNAs have been implicated in regulating expression of the HBA1 gene. Below is microarray data showing the amount of expression of different microRNAs where each row corresponds to the different miRNA indicated on the...
5. (2pts) a-thalassemia is a human genetic condition resulting in severe anemia because blood cells can not efficiently carry oxygen to body tissues. a-thalassemia occurs when the HBA1 gene is mutant such that no protein product is made or a non- functional protein is produced. Recently, microRNAs have been implicated in regulating expression of the HBA1 gene. Below is microarray data showing the amount of expression of different microRNAs where each row corresponds to the different miRNA indicated on the...
Genetics Worksheet Week 3: Gene Regulation and Epigenetics 1. Duchenne muscular dystrophy is caused by a mutation in a gene that is 2.5 million nucleotides in length and encodes a protein called dystrophin. The dystrophin protein itself is 3684 amino acids in length. Calculate below the approximate size of the mRNA that encodes dystrophin. Approximately what percentage of the gene that encodes dystrophin is intron sequence? The human genome encodes a much greater variety and number of proteins than the...
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