The reaction is given as follows,
malonic ester synthesis Target Product G. Click on a reactant to add it to the synthes...
synthesis of cyclic acetals
Target Product H₂C H2C CH3 click on a reagent to add it to the synthesis p (0.202 sec) Link Reload Reactants Reload Reagents Reload Pathway / Workspace Products Reactants CH3 0- нс о CH3 НО- он Н.С re.edugen.wiley.com/cgibin/tutorial/Reaction Tutorial Reactants он Н.С. -Сн, нс- нс 0 Н.С Сн. HS - HEC CH3 HS Reagents OH OS-OH O (catalyst) OH H₂O OSOH ! o (cold, dilute) H2 (excess) Pt or Pd or Ni Pathway (0.000 sec)
halogenation of a-carbons
Target Product CH3 нс, 0 Hgc Br Br CH3 O CH3 H3C click on a reagent to add it to the synthesis E (0.216 sec) Link Reload Reactants Reload Reagents Reload Pathway / Workspace Reactants CH CH, HC o CH CH, не -CH H.C. CH, не не CH, Reagents Br2 H3O+ (Acetic Acid) Br2 NaOH Review Examples Enolate Chemistry
10. Select the compound that can not be made using the malonic ester synthesis: O O OH MeO Оме OH Ph OH A. B. Ph C. D. 11. In general both the malonic ester and acetoacetate synthesis require the addition of dilute acid in order to generate the final product. Why? A. the alkoxy cation needs to be eliminated C. the ionized cation partitions to the aqueous layer B. the stabilized enolate adds a proton in the separatory funnel D....
Page 1 Synthesis using Carbonyl O-Substitution Chemistry Preamble This experiment involves the synthesis of target molecules using a-substitution chemistry. You are assigned two target molecules, one of which is best synthesized by an alkylation approach, while the other is best synthesized by an addition or condensation approach. You must do the following: 1. Perform a retrosynthetic analysis on the two target molecules assigned to you. In each case the organic starting material (what you have to work backwards toward) depends...
Synthesis using Carbonyla-Substitution Chemistry Preamble This experiment involves the synthesis of target molecules using a-substitution chemistry. You are assigned two target molecules, one of which is best synthesized by an alkylation approach, while the other is best synthesized by an addition or condensation approach. My two target molecules are number 2 and number 12 in the last page. You must do the following: 1. Perform a retrosynthetic analysis on the two target molecules assigned to you. In each case the...
What is the theoretical yield (in grams) and percent yield of your
triphenylmethanol product in this experiment? (Weight of
triphenylmethanol: 0.060g)
BACKGROUND AND THEORY The Grignard reaction was one of the first organometallic reactions discovered and is still one of the most useful synthetically. By reacting an organohalide (usually a bromide) with magnesium in ethereal solvent, carbon becomes a nucleophile. Grignard reagents are the starting points for the syntheses of many alkanes, primary, secondary, and tertiary alcohols, alkenes, and carboxylic...
Synthesis of 1-Bromobutane: An SN2 Reaction Pre-Laboratory
Exercises
PRE-LABORATORY EXERCISES NAME: Cynthesis of 1-Bromobutane: An SN 2 Reaction Butylbromide was prepared by refluxing in a 100-ml round bottomed flask a solution containing 13:35 Br 15 ml of water, 10 mL of n-butyl alcohol. 15 ml of concentrated H.SO. and a few boiling stories, 1. 2. R." d 1.275 laborales Nel CH3CH2CH2CH2OH + NaBr H2SO4 Superletalyst CHCH2CH2CHBr + NaHSO + HO (eq. 16) 1-butanol bp 118 C 1-bromobutane d 0.810 bp...
i need help with the postlab questions please
Grignard reagent THE GRIGNARD REAGENT-PREPARATION AND REACTION In this experiment, you will prepare a Grignard reagent, phenyl magnesium bromide, from bromobenzene and magnesium metal. The Grignard reagent will then react with methyl benzoate to form triphenylmethanol. Introduction Grignard reagents, such as organomagnesium halides, were discovered in 1910 by French chemist Victor Grignard. The Grignard reaction is one of the most general methods for carbon- carbon bond formation in all of organic chemistry....