This is a nucleophilic addition reaction.
Aldehydes or ketones reacts with organolithium to give alcohols. In this reaction organolithium adds to ketones to give tertiary alcohols. The acidic work up converts the intermediate metal alkoxide salt into the corresponding alcohol.
What is the major product of this reaction? CH3Li H20*, H2O
Question 35 (4 points) What is the major product of this reaction? CH3Li H2O*, H20 OH d H 애
Question 30 (4 points) What is the major product of this reaction? CH3Li H2O5, H20 OH ot w OH OH of
Draw the major product of the following reaction. 1. CH3Li O 2. H20 Create OscerSketch Answer 6
Draw the major product of the reaction sequence. Omit byproducts OH 1) HOCH2CH2OH, pTSOH 2) CH3Li, then H2O* 3) cat. H2SO4 4) H20. pTSOH 5) Isopropyllithium, then H30* 0
What is the major product of this reaction? CH3Li H2O*, H2O
what is the major product of the following reaction? What is the major product of the following reaction? 1. excess CH2CH2MgBr 2. H30* Product OCH, OH OCH; OH OH OCH + CH3OH + H20 + CH,OH
Draw the major organic product formed when the compound shown below undergoes a reaction with CH3Li and then is treated with water. CH 3
12. What would be the major product of the following reaction? i. Brz, NaOH ii. H20" ? mo Br НО. O II III Br Br ho IV A. I B. II C. III D. IV E. V 13. What would be the major product of the following reaction sequence? A. I B. II C. III D. IV E. V 2 i. LDA ii. CHEI De ci II I III IV V 14. Which of the following could be used to...
Draw the major product for each reaction. он. CH3 heat N(CH3)3 a. LiAIH4, Et20 b. H30*/H20 1. NaCN, DMSO Br 2. a. LiAIH4. THF b. H3O+/H2O 1. NaN3, DMSO Br 2. a. LiAIH4, THF b. H3O /H20 1. HNO3, H2SO4 2. SnCl2 3. Br2 4. a. HNO2, H2SO4 H3C b. H2PO2 NH2 1. NaNO2, HCI, H20 но 2. HBF4