Question

QUESTION 27 These unusual bacterial toxins interact with and activate exceedingly large numbers of T-lymphocytes resulting in excessive production of IL-2. This, in turn, can lead to production of inflammatory cytokines such TNF-alpha, IL-1, inflammatory chemokines such as IL-B, and platelet-activating factor or PAF, and potentially lead to SIRS. This best describes what? Type Il toxins that interfere with host cell functions Type I toxins (superantigens) Bacterial endotoxin Type Il toxins that damage cell membranes Promiscuous slut toxins

Answer 1

In this case, the correct answer is Type I toxins (superantigens) which are able to directly bind to the MHC-II molecules, activating T4-lymphocytes. In fact, these superantigens are able to activate a large number of T4-lymphocytes leading to a increased secretion of IL-2. Additionally, It also activates self-reactive T-lymphocytes.