Question

Choose the best match for this item:

Sickle cell shape

A. Decreased oxygen

B. Variant forms of hemoglobin

C. Blood hemoglobin level

D. Hgb E

E.Homozygous

F. Hgb F

G. CLIA waived

H. Hgb A1

I.Thalassemias

J. Carrier

Answer 1

Sickle cell shape:

Variant forms of haemoglobin is the best match because Sickle cell anemia is a disease of RBCs in which the shape of the RBCs is changed from a disc to a sickle shape because of the replacement of normal HbA gene of haemoglobin to HbS gene. This changes the 6th place of beta globin chain from Glutamine to Valine.