Question

QUESTION 63 The reason that uninfected cells are not harmed by acyclovir is: A healthy cells lack the ability to even take acyclovir into the cell OB. normal cells lack a thymidine kinase gene (TO) OC. acyclovir targets the spike protein of viruses OD. acyclovir is inactivated by the kinases of uninfected cells E acyclovir inhibits RdRp which normal cells lack QUESTION 64 Which of the following viruses causes chickenpox and shingles: OA. human herpes virus B. papillomavirus OC. herpes simplex virus OD. poliovirus E. B19 parvovirus OF. rhinovirus G.rotavirus OH. Epstein-Barr virus OL varicella zoster virus J. cytomegalovirus

Answer 1

Ans63:- b) normal cells lack thymidine kinase gene.

concept:- actually acyclovir is present in inactive form in normal cell. It is only activated in viral infected cell due to presence of thymidine kinase which is encoded only by virus infected cell.

Thymidine kinase convert acyclovir to acyclovir monophosphate .

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Ans 64:- L ) vericella zoster virus >> c) herpis simplex virus

Shingles is caused by the varicella-zoster virus — the same virus that causes chickenpox.

Human alphaherpesvirus 3, usually referred to as the varicella-zoster virus.

Actually the frist infection with varicella virus causes chicken pox ... Once chicken pox is corrected this virus remain in dormant state in geserion ganglion.

In old age when immune system weakens them this virus reactivate and cause shingles.

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