Question

1. True and False Question (0.5 point per question)

a) Carbonyl compounds have higher boiling points than hydrocarbons, but lower boiling points than corresponding alcohols.

b) Aldehydes and ketones react with primary amines to form imines and with secondary amines to form enamines.

c) Aldehydes and ketones can be oxidized to carboxylic acids.

d) Diols can form acetal with the ketone or aldehyde to protect them for selective reduction of the ester.

e) The electron-withdrawing group in Wittig reagent does not impact the configuration of the product.

f) Both Wittig reaction and Horner-Wadsworth-Emmons (HWE) reaction generate E-alkenes as the major product.

g) In the Baeyer-Villiger oxidation, the carbon migration will take place in both symmetric and asymmetric ketone or aldehyde.

h) In the Baeyer-Villiger oxidation, migratory aptitude follows the following order: H > 3° alkyl > 2° _alkyl ≈ _phenyl > 1° _alkyl > methyl.

i) In IR spectrum, carbonyl (C=O) groups give a strong peak for C=O stretch between 1670-1820 cm-1, and the peak position is impacted by conjugated structure and ring structure.

j) The formation of carboxylate salts increases the water solubility of carboxylic acids.