NaOCH3 gives OCH3- which is a strong base and it abstracts the most acidic proton.
Thereafter the anion(formed upon acid-base reaction in last step) undergoes SN2 reaction with given alkyl bromide.As this is SN2 reaction, so it will be favoured much at the position where least hindrance is present.During this SN2 reaction, the anion attacks (from backside) at the carbon to which least hindred bromine is connected.
Remember the configuration of dark bond(chiral carbon) will not change
After this ester hydrolysis takes place and ester is converted to carboxylic acid.
and Upon heating CO2 leaves.
provide product for following mechanisms shown 1. NaOCH, 1. H, 2. heat حمله Page 1 of...
24. Provide the major organic product in the reaction shown below. Ph Br -н NaOCH Hас- H Ph 25. Provide a series of steps through which 2-methylbutane is converted into 2-methylbut-1-ene.
Provide the major organic product of the following reactions. *CO2CH3 1. NaOCH 2. Hz0+ CO2CH3 Draw the molecule on the canvas by choosing buttons from the Tools (for b bond is active by default. H: 120 EXP CONT a +
provide mechanisms for the following H₂O+ heat ОН А в с
(10 pts) Predict the major product for each of the following reactions. 2. Ho Br 1. NaOH/Br 2. H,O NaOH/H20 1. NaOCH,CH 2. H,0 1. NaOCH,CH, 2 HO (10 pts) Predict the major product for each of the following reactions. 2. Ho Br 1. NaOH/Br 2. H,O NaOH/H20 1. NaOCH,CH 2. H,0 1. NaOCH,CH, 2 HO
59. Provide the major organic product in the reaction shown below. 1. NH4 2. KOH, heat 0 3. H20 60. O= 1. NH2NH2 H₃C 0 CH2 CH3 2. "OH, heat ii. What is the reactant W in the synthesis given below? a) Cyclopentanone b) Cyclopentene c) Cyclopentanol d) Bromocyclopentane e) Triphenylphosphine oxide What is the final product of this synthetic sequence? | Br2 Mg 1. C,H,CHO H Cr,04 Benzene FeCl, ether 2. H,0 acetone d) e) CHECCHS p-BrC.H.CH.C.HSCH:CHCOOH CA HECH,...
show mechamsim RU, n20, neat 83. Provide the major organic product of the following. Section CH (CO2CH3)2 1. NaOCH 2. BICH, CH CH CH Br 3. NaOCH 4. Hz0.A
Provide the major organic product in the reaction shown below. Ph NaOCH нас Ph
4. Provide the products of each reaction (3pts, 2pts) 1. H2O+ OCH; 2. NaOCH, CHOH OCH 3. H, A 4. NaCN 1. LDA 2. Pho 3. H , A 4. EtMgBr 5. Provide an arrow-pushing mechanism for the reaction below, and state how many product stereoisomers are possible (5 pts) NO2 cat. KOH ЕКОН
4. Provide the products of each reaction (3pts, 2pts) 1. H,O* OCH; 2. NaOCH, CHOH OCH, 3. H, A 4. NaCN 1. LDA 2. Pho 3. H , A 4. EtMgBr
Problems: 2) Provide the missing product(s) or reagents for these reactions. (28 pt) CH2OCH2CH3 CH2Br NaOCH CH CO2H Br OTs KOH Hydrazine Phthallimide Heat