4. Below is an example of a well-known electrophilic aromatic substitution reaction from the choices below circle the structure, which represents the electrophile. (2 points)
4. Below is an example of a well-known electrophilic aromatic substitution reaction from the choices below...
this is a electrophile aromatic substiution reaction. circle which structure represents the electrophile AICI, A. B. :c: C. : Cl : D. E. None of the above
250 ChemActivity 29 Electrophilic Aromatic Substitution no ChemActivity 29 Part A: Electrophilic Aromatic Substitution (What products are formed when a strong electrophile is added to benzene?) Model 1: (review) Electrophilic Addition of HCI Rani o g cyclohexene carbocation intermediate Run 2 U X benzene This product carbocation intermediate DOES NOT Critical Thinking Questions 1 For Rxn I (above) draw curved arrows showing the mechanism of electrophilic addition of HCl. Include an appropriate carbocation intermediate in the box above. Figure 1:...
Nitration of an aromatic ring involves an electrophilic substitution reaction. Draw the structure of the electrophile that is attacked by the aromatic ring and the intermediate formed after attachment of the electrophile to the ring. Be sure to show formal charges.
Aromatic heterocycles also undergo electrophilic aromatic substitution reactions. When furan is treated with an electrophile, the electrophile is installed only at the C-2 position. Explain why this reaction occurs only at the C-2 position, rather than the C-3 positions.(explain in words and resonance structures) Question 2 (10 pts). Aromatic heterocycles can undergo EAS reactions. When furan (below) is treated with an electrophile, an EAS reaction occurs in which the electrophile is installed only at carbon 2, not carbon 3. Explain...
Create and show an example of two Electrophilic Aromatic Substitution mechanisms shown below: Show the full mechanism. Thank you. (leave out the activation of the electrophile) 1) Alkylation: 2) Acylation:
3. The electrophilic aromatic substitution (EAS) reaction is a great way to prepare substitute Provide the expected major product for each of the following EAS reactions. (12 pts) SO3H HNO3 H2SO4 CH2CH3 CI AICI en Enhen II Ph-C-NHÓh Br2 CH3 -CH₃ CH3 FeBr3
a) Complete the generic mechanism for an electrophilic aromatic substitution (EAS) reaction using El as the electrophile and show how the sigma complex is resonance stabilized. Use curved arrows to show the mechanism and the conversion between resonance structures. Make sure to add any missing charges. Note the use of a generic base in the last step. b) Label the reaction coordinate diagram for a typical EAS reaction shown below by correctly placing the letter for each structure on the...
4. In Chapter 18 we will learn about the electrophilic aromatic substitution reaction shown below. structure of the product of the reaction based on the data given below Predict the Br2 AlBr3 Product Molecular Formula: CH1302Br Calculate the units of unsaturation-(2C+ N + 2-X-H)/2 where X is any halogen. 13C NMR (ppm): 9.7, 19.9,29.5, 73.6,123.0, 128.9, 129.6,132.0, 132.3,135.9,165.9 List at least one thing you can learn from the 13C NMR data Indicate the functional group and specific bond that each...
6. (9 pts) In regards to an electrophilic aromatic substitution reaction, define the 3 compounds shown below as either: a) Activating, ortho, para director b) Deactivating, ortho para director, c) Activating, meta director, d) Deactivating, meta director. CH -ОН -N-CH3 CH3 7. Answer a-c for compounds A-F below dos a. (5 pts) Which compound(s) have an aromatic carbocation intermediate if it underwent an Snl or E1 reaction? b. (5 pts) Which compound(s) would have an anti-aromatic carbocation intermediate if it...
Which compound is the least reactive in the aromatic electrophilic substitution reaction? What product would you expect from the following reaction? Answer both, please. 1. Which compound is the least reactive in the aromatic electrophilic substitution reaction? NH . B NH С. SOH Logo D. NO2 E 2. What product would you expect from the following reaction? CO.CH ÇO.CH А ÇOCH B OCH, D CO.CH E