Question

S - Truckee Meado Bachelor of Science in Kinesiology Academics... Quiz: Ex-MC-EC Community Health Science, AS - Truckee Meado.. Question 5 1 pts which is/are Integral membrane proteins typically contain substantial sections of and therefore can interact with the sections of the lipid bilayer. o ООО alpha helix // nonpolar // hydrophobic polar, uncharged amino acids // polar // interior charged amino acids // nonpolar // hydrophobic charged amino acids // polar // interior polar, uncharged amino acids // polar // hydrophobic Question 6 1 pts One type of biochemical pathway regulation is negative feedback inhibition. This process (select all that are true) includes cooperative binding of a substrate to an enzyme increasing the binding of more substrate accelerates the production of a product shuts down glycolysis at the phosphofructokinase enzyme if ATP concentration is high reduces the buildup of a product if the product acts as an enzyme activator early in the pathway reduces the buildup of a product if the product acts as an allosteric inhibitor early in the pathway 12,600

Answer 1

•Answer 5:- integral membrane protein are attached permenantly to the biological membrane that cross the membrane are surrounded by annular lipids. The part of the protein that is embedded in the hydrophobic regions of the bilayer are alpha helical and composed of predominantly hydrophobic amino acids. The C terminal end of the protein is in the cytosol while the N terminal region is in the outside of the cell. So your answer is option 1 = alpha helix//nonpolar// hydrophobic.

•Answer 6:- feed back inhibition is a mechanism in which the product itself act as a inhibitor that stops the on going process. There are various examples of feedback inhibition. A good example in bacteria is tryptophan operon, in this, the tryptophan amino acid itself bind to the operator site and stop the operon from the protein synthesis process. Another example is hormones in human :- In the male with rising levels of testosterone acting on the hypothalamus and anterior pituitary to inhibit the release of GnRH, FSH, and LH. ATP is a natural allosteric inhibitor of PFK, in order to prevent unnecessary production of ATP through glycolysis. A high level of ATP inhibits the enzyme by decreasing its affinity for fructose 6-phosphate. AMP diminishes and citrate enhances the inhibitory effect of ATP. Here are two options which are your correct answer-

1.Shut down glycolysis at the PHOSPHOFRUCTOKINASE [PFK] enzyme if ATP conc. is high.

2.Reduces the building up of product , if it act as an allosteric inhibitor , early in the pathway.