Question

Theophylline, a methylxanthine, is used to treat asthma. Explain the mechanism by which a theophylline can...

Theophylline, a methylxanthine, is used to treat asthma. Explain the mechanism by which a theophylline can alleviate asthma symptoms resulting from bronchial constriction (think of a pathway cAMP is involved in).

0 0
Add a comment Improve this question Transcribed image text
Answer #1

Theophylline helps in relaxing the smooth muscles which tightens to cause bronchial constriction. It also helps in relaxing pulmonary vessels & decreases the airway responsiveness towards adenosine, histamine, methacholine & allergen. The methylxanthine drug totally blocks type III & IV PDE (phosphodiesterase). PDE is an enzyme which breaks down cAMP in cells of the smooth muscles. Thus, an increased cAMP in the smooth muscles cells, helps in muscle relaxation.

hope the answer helps.

Add a comment
Know the answer?
Add Answer to:
Theophylline, a methylxanthine, is used to treat asthma. Explain the mechanism by which a theophylline can...
Your Answer:

Post as a guest

Your Name:

What's your source?

Earn Coins

Coins can be redeemed for fabulous gifts.

Not the answer you're looking for? Ask your own homework help question. Our experts will answer your question WITHIN MINUTES for Free.
Similar Homework Help Questions
ADVERTISEMENT
Free Homework Help App
Download From Google Play
Scan Your Homework
to Get Instant Free Answers
Need Online Homework Help?
Ask a Question
Get Answers For Free
Most questions answered within 3 hours.
ADVERTISEMENT
ADVERTISEMENT
ADVERTISEMENT