Question

Scientists have found that extracellular matrix components may induce specific gene expression in embryonic tissues such as the liver and testes. For this to happen there must be direct communication between the extracellular matrix and the developing cells. Which kind of transmembrane protein would most likely be involved in this kind of induction?

Answer 1

Extracellular Matrix (ECM):-- - Although Animal cell are not surounded by cell wall many of cell in tissue of multicellular organism are embeded in an extre-cellular matrix consisting of secreated protein and polysachasids. The extracellular matrix fills the space between cell and bind call and tissue togather one type of extrue ellular matrix is exemplifed by the thin sheetlike basal laninae of basements membrane upon which layer of epithalial cell resp In addition to supposting Sheet or epithelial cell basal laminae surrounded muscle cell adipose tissue cell and peripheral nerves. Extracellular matrix howeves is most abandant in connective tissue. for example the loose connective tissue beneath epithalial cell layers consist predominantly otun extracellular matrix in which fibroblast are distributed other type of connective tissue such as bone tendon and cartilage similarly consist largely of extracellular matrin which is principally responsible for rhonsible for their structure and function . - Extracellular matrix are composed of tough fibrous protein embeded in a gel like puly Suchaside ground substance. In addition to fibrous structure -protein and polysacharide the extracellular matrin conterin adhesion protein that link components of the matrix both to one another and attached to cell. - The major structural protein of ECM. is Collagen which is single most aboundant protein in animal tissue the collagen are large family protein, C Conneetive tissue also contain elastin biber which are particularly aboundout in organ that seqularly Stretch and then return to their orignal Shape eg-Lung Elastin fiber composed principolly of a prore in called Elastin the fibrous struatural protein of Ecm are embeded gul form polysacharide called slycosaminoglycanCGAGS which consist repetete unit of disacharide.