Question

The following compound has stereogenic centers at c-3 and c-s. Assign the configurations for C.3 and 2.5 for the enantiomer of the following compound. OH

Answer 1

For assign R and S absolute configuration for the given molecule we have follow some rules.

• Find the chiral center for which you have to assign .Then start giving number with their respective priority.Priority depends on the masses or atomic number.
• If some have higher atomic mass give them hai 1 priority similarly label all.
• After labelling make sure that the lowest priority group is away from the observer means in the dashed notation.Then start rotation from sequence wise like 1-2-3-4 .If the rotation is clockwise assign R if counterclockwise assign S.
• After labelling if the lowest priority group is on the wedge the after rotation along priority bases if you get clockwise rotation assign S or counterclockwise rotation assign R.

gunem ics At C- anti clockwise = S but -örn =) = R At C-5 1H 애 ㅕ anticlockwise rotation zs Scanned with ÇamScanner