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The second step of the synthesis transformation of the chlorosulfonyl functional group into a sulfonamide) is an example of a

THE SULFONIC ACID GROUP AND ITS DERIVATIVES Sulfonic acids are organic analogs of sulfuric acid, a very strong acid. They are

This makes it apparent why aniline cannot be used as the starting material in the synthesis. The amine group is a strong elec

3. FORMATION OF THE SKMA COMPLEX A RESONANCE STABILIZED REACTION INTERMEDIATE (structures I-IV). NHCOCH3 NHCOCH3 NHCOCH3 NHC

NH3 O=o=0 H3COH 5. REACTION OF SULFONYLCHLORIDE GROUP WIIH A NUCLEOPHILE(AMMONIA). Aryt (aromatic) group (AN) H3COCHN SOCI =

7. PROTECTING GROUP SIRATEGY-Acetanilide is used as the starting material in these reactions, but at the end the amide group

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