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In a differential scanning calorimetry experiment, the melting temperature, Tm, of a certain protein is found...

In a differential scanning calorimetry experiment, the melting temperature, Tm, of a certain protein is found to be 46 C and the enthalpy of denaturation is 382 kJ/mol.

a. Estimate the entropy of denaturation assuming that the denaturation is a two-state process; that is: native protein<=>denatured protein.

b. The single polypeptide protein chain has 122 amino acids. Calculate the entropy of denaturation per amino acid. Comment on your results.

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Answer #1

I Aus - Given Tm = 46°c ( melting temperature) AH = 382 kg/mes (enthalpy of denaturation) AS = 2 (en that by of entropy chang

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