![4. List two different sets of reagents (each set consisting of a carbonyl compound and a Grignard reagent) that could be used to synthesize each of the following secondary alcohols. [4 points each] 3H 5. Reaction of cyclohexanone with ethylene glycol in the presence of an acid catalyst gives the cyclic acetal shown. Propose a mechanism for this reaction. [8 points]](http://img.homeworklib.com/questions/2e015fb0-4cb3-11eb-8a10-a312510023b0.png?x-oss-process=image/resize,w_560)
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4. List two different sets of reagents (each set consisting of a carbonyl compound and a...
Problem 1. Synthesize the following alkene through the Wittig reaction of a carbonyl compound and a...
Problem 1. Synthesize the following alkene through the Wittig reaction of a carbonyl compound and a Wittig reagent. 2,3-diphenyl-2-butene 2. Predict the products of the following reactions. Casco CHCH.CHCH, CHCH.CH но ats ОО 2.0 CH,CHACHCH,CHCHOCH.CH, CH 3. A useful and general method for the synthesis of alcohols is the addition of Grignard reagents to carbonyl compounds. Show what Grignard reagent and what carbonyl compound you would start with to prepare the alcohol below. List all possibilities. 2-methyl--butanol 2-METHYL-2- BOTANIC
organic chemistry 3. The starting material below forms a six-membered cyclic hemiacetal in an aqueous solution:...
organic chemistry
3. The starting material below forms a six-membered cyclic hemiacetal in an aqueous solution: (pis) r , " a) Name the starting material b) Draw the mechanism of the reaction above. Note the role of H". c) How many stereoisomers are possible for the starting material? d) How many stereoisomers are possible for the cyclic hemiacetal? 4. Propose a mechanism for the formation of the cyclic acetal by treating acetone with ethylene glycol in the presence of an...
Give three different sets of reagents (a carbonyl compound and a Grignard reagent) that could be...
Give three different sets of reagents (a carbonyl compound and a Grignard reagent) that could be used to prepare the following compound. OH CH3-C-CH2CH3 CH3 Check all that apply Check all that apply. CH3 CH2 COCHg and CH3 MgBr CH, CH2 COCH3 and 2CH3 MgBr CH3 CH2 C CH3 and CH3 MgBr CH3 C CH3 and CH3CH, MgBr 0 CH3 C OCHZ and CH3CH, MgBr CH3CH, C CH3 and 2CH3 MgBr Submit Previous Answers Request Answer
8. Give the Grignard and Carbonyl compound needed to make each of alcohols. (6 points, 2...
8. Give the Grignard and Carbonyl compound needed to make each of alcohols. (6 points, 2 each) nd needed to make each of the following you - 9. Circle the compounds that could not be made into a Grignard Reagent. Br 10. Show how you could convert the compound below into a Grignard reagent without having it destroy itself. (4 points)
Grignard reagents are used to make C-C new bonds. Their reaction with carbonyl compound leads to...
Grignard reagents are used to make C-C new bonds. Their reaction with carbonyl compound leads to alcohols. However, when reacted with carboxylic acids carbonyl compounds are formed. Predict what should be the product of the reaction between 4-nitrobenzoic acid and phenyl magnesium bromide and explain in few chosen words why a carbonyl compound instead of an alcohol.
What two sets of reagents (each consisting of a carbonylcompound and phosphonium ylide) can be...
What two sets of reagents (each consisting of a carbonyl compound and phosphonium ylide) can be used for the synthesis of each of the following alkenes?What alkyl halide is required to prepare each of the phosphonium ylides?What is the best set of reagents to use for the synthesis?
1. (6 pts) Provide two different syntheses for 1,1-diphenyl-1-butanol starting from a carbonyl compound and using a...
1. (6 pts) Provide two different syntheses for 1,1-diphenyl-1-butanol starting from a carbonyl compound and using a Grignard reagent. Synthetic Route 1: carbonyl Grignard reagent a) THE b) H30* work up 1,1-diphenyl-1-butanol Synthetic Route 2: carbonyl Grignard reagent a) THF b) H30* work up ОН 1.1-diphenyl-1-butanol 2. (3 pts) The use of Grignard reagents requires scrupulously dry aprotic solvents such as diethyl ether or tetrahydrofuran. Please explain why the solvents need to be scrupulously dry. To support your reason, show...
Rank the following group of compounds from most acidic (1) to least acidic (4). Place the...
Rank the following group of compounds from most acidic (1) to least acidic (4). Place the number corresp the compound's relative rank in the blank below the structure. (4 points) 2. (CF3)2CHOH CH3CH OH 3. Predict the product of the following reaction. (6 points) heat and general method for the synthesis of alcohols is the addition of Grignard reagents to ca Show what Grignard reagent and what carbonyl compound you would start with to prepare each 4. A high below....
help with 23 HAPTER 14: ORGANOMETALLIC COMPOUNDS TWO common solvents for Grignard reagents are: 1) ethanol...
help with 23
HAPTER 14: ORGANOMETALLIC COMPOUNDS TWO common solvents for Grignard reagents are: 1) ethanol and diethyl ether. 2) diethyl ether and tetrahydrofuran (THF). 3) tetrahydrofuran (THF) and toluene. 4) water and ethanol. What is the product of the following reaction? CH, CH. CHCH.CH - ether 2) 2-ethyl-1-pentanol 2) 2-ethyl-1-butanol 3) 3-pentanel 4) 3-aethyl-1-pentanc: The reaction of benzyl sagnesius bromide (C.HSCHMB) with acetaldehyde (CHC40) followed by hydrolysis yields: 1) 1-phenyl-1-propanol 2) 1-phenyl-2-propanol 3) 2-phenyl-2-propanel 4 .-ghen -propane: mo synthesize...
3. Provide a full arrow-pushing mechanism for each of the following reactions. Но, он НО Но...
3. Provide a full arrow-pushing mechanism for each of the following reactions. Но, он НО Но он і - H- 0ң но он Насо, осна Нt H2O 4. A researcher wants to run the following sequence of reactions. However, they know starting Grignard reagent cannot exist due to the presence of its reactive carbonyl group. MgBr H.H cannot exist! An acetal group can be used to protect" a carbonyl from attack, allowing it to survive otherwise incompatible reaction conditions. Provide...
Problem 1. Synthesize the following alkene through the Wittig reaction of a carbonyl compound and a Wittig reagent. 2,3-diphenyl-2-butene 2. Predict the products of the following reactions. Casco CHCH.CHCH, CHCH.CH но ats ОО 2.0 CH,CHACHCH,CHCHOCH.CH, CH 3. A useful and general method for the synthesis of alcohols is the addition of Grignard reagents to carbonyl compounds. Show what Grignard reagent and what carbonyl compound you would start with to prepare the alcohol below. List all possibilities. 2-methyl--butanol 2-METHYL-2- BOTANIC
organic chemistry
3. The starting material below forms a six-membered cyclic hemiacetal in an aqueous solution: (pis) r , " a) Name the starting material b) Draw the mechanism of the reaction above. Note the role of H". c) How many stereoisomers are possible for the starting material? d) How many stereoisomers are possible for the cyclic hemiacetal? 4. Propose a mechanism for the formation of the cyclic acetal by treating acetone with ethylene glycol in the presence of an...
Give three different sets of reagents (a carbonyl compound and a Grignard reagent) that could be used to prepare the following compound. OH CH3-C-CH2CH3 CH3 Check all that apply Check all that apply. CH3 CH2 COCHg and CH3 MgBr CH, CH2 COCH3 and 2CH3 MgBr CH3 CH2 C CH3 and CH3 MgBr CH3 C CH3 and CH3CH, MgBr 0 CH3 C OCHZ and CH3CH, MgBr CH3CH, C CH3 and 2CH3 MgBr Submit Previous Answers Request Answer
8. Give the Grignard and Carbonyl compound needed to make each of alcohols. (6 points, 2 each) nd needed to make each of the following you - 9. Circle the compounds that could not be made into a Grignard Reagent. Br 10. Show how you could convert the compound below into a Grignard reagent without having it destroy itself. (4 points)
Grignard reagents are used to make C-C new bonds. Their reaction with carbonyl compound leads to alcohols. However, when reacted with carboxylic acids carbonyl compounds are formed. Predict what should be the product of the reaction between 4-nitrobenzoic acid and phenyl magnesium bromide and explain in few chosen words why a carbonyl compound instead of an alcohol.
1. (6 pts) Provide two different syntheses for 1,1-diphenyl-1-butanol starting from a carbonyl compound and using a Grignard reagent. Synthetic Route 1: carbonyl Grignard reagent a) THE b) H30* work up 1,1-diphenyl-1-butanol Synthetic Route 2: carbonyl Grignard reagent a) THF b) H30* work up ОН 1.1-diphenyl-1-butanol 2. (3 pts) The use of Grignard reagents requires scrupulously dry aprotic solvents such as diethyl ether or tetrahydrofuran. Please explain why the solvents need to be scrupulously dry. To support your reason, show...
Rank the following group of compounds from most acidic (1) to least acidic (4). Place the number corresp the compound's relative rank in the blank below the structure. (4 points) 2. (CF3)2CHOH CH3CH OH 3. Predict the product of the following reaction. (6 points) heat and general method for the synthesis of alcohols is the addition of Grignard reagents to ca Show what Grignard reagent and what carbonyl compound you would start with to prepare each 4. A high below....
help with 23
HAPTER 14: ORGANOMETALLIC COMPOUNDS TWO common solvents for Grignard reagents are: 1) ethanol and diethyl ether. 2) diethyl ether and tetrahydrofuran (THF). 3) tetrahydrofuran (THF) and toluene. 4) water and ethanol. What is the product of the following reaction? CH, CH. CHCH.CH - ether 2) 2-ethyl-1-pentanol 2) 2-ethyl-1-butanol 3) 3-pentanel 4) 3-aethyl-1-pentanc: The reaction of benzyl sagnesius bromide (C.HSCHMB) with acetaldehyde (CHC40) followed by hydrolysis yields: 1) 1-phenyl-1-propanol 2) 1-phenyl-2-propanol 3) 2-phenyl-2-propanel 4 .-ghen -propane: mo synthesize...
3. Provide a full arrow-pushing mechanism for each of the following reactions. Но, он НО Но он і - H- 0ң но он Насо, осна Нt H2O 4. A researcher wants to run the following sequence of reactions. However, they know starting Grignard reagent cannot exist due to the presence of its reactive carbonyl group. MgBr H.H cannot exist! An acetal group can be used to protect" a carbonyl from attack, allowing it to survive otherwise incompatible reaction conditions. Provide...
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