During exercise when the body lacks an adequate supply of oxygento support energy production, the...

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During exercise when the body lacks an adequate supply of oxygen to support energy production, the pyruvate that is produced from the breakdown of glucose is converted into lactate. High lactate levels can lead to acidity in the muscle cells as some of the lactate hydrolyzes to lactic acid.

The dissociation of lactic acid to lactate is shown in the reaction. Lactic acid has a pKa of 3.86

During exercise when the body lacks an adequate supply of oxygen to support energy production, the pyruvate that is produced

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Answer 1

Answer #1

Since lactic acid is a weak acid and lactate ions is its conjugate base, they together act as buffer solution.

Lactic acid (weak acid) <-----> Lactate(Conjugate base) + H⁺(aq) ; pKa = 3.86

Given pH of the buffer solution = 3.29

pKa = 3.86

Applying Henderson equation:

pH = pKa + log([Conjugate base] / [Acid])

=> 3.29 = 3.86 + log([Lactate]/[Lactic acid])

=> log([Lactate]/[Lactic acid]) = 3.29 - 3.86

=> log([Lactate]/[Lactic acid]) = - 0.57

Taking power of 10 to both sides

=> [Lactate]/[Lactic acid] = 10^-0.57

=> [Lactate]/[Lactic acid] = 0.269 (Answer)

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Answer 2

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