Question

Signal amplification is an essential step in signal transduction. Which of the following steps of signal...

Signal amplification is an essential step in signal transduction. Which of the following steps of signal transduction amplify the signal (select all that apply)?

Group of answer choices

a) ligand binding to receptor

b) release of GTP bound form of G protein from receptor

c) binding of GTP bound form of G protein to target enzyme

d) generation of second messenger by activated target enzyme

e) activation of gene expression

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Answer #1

1. Option a. Ligand is bound to the receptor

2.Option c. the receptor is activated when GDP is replaced by GTP. In GDP bound form the receptor is inactive. In GTP bound state the receptor is active.

3. Option d. Secondary messenger is generated by the active target enzyme.

4. Option e. Gene expression is upregulated by the activation of the secondary messenger.

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