Question

1. A clinical trial is planned to compare an experimental medication designed to lower blood pressure to a placebo. Patients are enrolled and randomized to either the experimental medication or the placebo. The data shown below are data collected at the end of the study after 6 weeks on the assigned treatment.

	Experimental (n=100)	Placebo (n=100)
Mean (SD) Systolic Blood Pressure	120.2 (15.4)	131.4 (18.9)
% Hypertensive	14%	22%
% With Side Effects	6%	8%

            Is there a significant difference in the mean systolic blood pressures between groups?         Use α = .05.

Step 1.           Set up hypotheses and determine level of significance

                       

Step 2.             Select the appropriate test statistic

                                               

Step 3.             Set up decision rule

                       

Step 4.             Compute the test statistic.

           

            Step 5.            Conclusion

Answer 1

Given 120.2 18-g tedence n he mean li dses etocen apodgpi stepi Hypodheses ave Step-2-Test stafistics tcal 20.2 tca 2 43797 4 S939 .9720 Concuuron tab ve sefest Ho at o.os can Sau e egence in dne mean rc blood foesr wer getoeengop