Question

Draw an action potential on a graph showing the x-axis and y-axis with proper labels and numbers (the numbers are approximate as they may vary slightly from neuron to neuron). A. Describe the ionic conductances that underlie the action potential including gating of the specific ion channels at threshold, rising phase, falling phase and the undershoot phase. Explain threshold, absolute refractory period and relative refractory period in relation to the action potential. B. C. Sodium and potassium currents demonstrate very different kinetics and yet, in the figure below, the data from sodium and potassium look virtually identical. Explain what is being measured in this figure and how that can be reconciled with the differences in the currents that Hodgkin and Huxley measured in the squid giant axon during an action potential. 20 15 10 40 30 20 10 Na 80-60-40-20 020 40 -80 -60 -40 -20 0 20 40 Membrane potential imV Membrane potential (mV

Answer 1

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