1) Flaccid Paralysis:
- The paralysis observed here is the Flaccid paralysis, causing weakness and reduced muscle tone due to reduced release of the acetylcholine neurotransmitter at the neuromuscular junction.
2) The botulism toxin prevents the releases of Acetylcholine neurotransmitters at the neuromuscular junction, causing them to stop the signaling from CNS to the skeletal muscles causing paralysis.
3)
- Respiratory problems: The respiratory problems arises due to the inactivation of the muscles of respiration, mainly the intercostal muscles.
- For the contraction of respiratory muscles, it requires acetylcholine to be released from presynaptic neurons and combines the Nm receptor of the muscle fibers to cause their contraction. Botulism toxin reduces the activity of Acetylcholine resulting in respiratory problems.
Difficulty in swallowing and breathing
- The cranial nerves control the swallowing which is the first to get affected by Botulin toxin. The acetylcholine neurotransmitter is inhibited, resulting in no communication between the neurons and muscles that help in chewing and swallowing, causing difficulty in swallowing and breathing.
Tim Canner improperly canned some home grown vegetables and contracted botulism poisoning after eating them. The...
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