Which of the following alcohols would undergo Sn2 substitution to an alkyl halide (using HBr) the fastest? Explain.
CH3CH2CH(OH)CH3b. CH3CH2CH2OHc. (CH3)3COH
answer is
b. CH3CH2CH2OH
because sterically free as compared to seconadr and tertiary alcohol.due to stericlly free ,the nucleophile can easily attacks from back side while leavig the OH^-1 from front side. that is posible only in primary alcohol.
so b .CH3CH2CH2OH is a primary alcohol so is very fast react towards SN^2 REACTION.
Which of the following alcohols would undergo Sn2 substitution to an alkyl halide (using HBr) the...
Which of the following alkyl halide will not undergo Sul or Sn2 reaction?
Which of the following alkyl halide will not undergo
SN1 or SN2 reaction?
PA
Which alkyl halide in each of the following reactions will react faster in an SN2 reaction with hydroxide (-OH)? Explain. Hint, some of these compounds are unreactive in SN2 reactions- be sure to think about what type of alkyl halide undergoes SN2 reactions! Bromobenzene or benzyl bromide CH3Cl or (CH3)3Cl CH3CH=CHBr or H2C=CHCH2Br
11. Which of the following alkyl halides will undergo the fastest SN2 reaction? < <===- ய
Which alkyl halide shown below would react the fastest under typical SN2 conditions?
3. Do primary alcohols undergo rearrangement upon conversion to the alkyl halide? Explain why or why not. Draw a mechanism or intermediates to help explain.
3. Do tertiary alcohols undergo rearrangement upon conversion to the alkyl halide? Explain why or why not. Draw a mechanism or intermediates to help explain.
c. The reaction of triphenylphosphine with an alkyl halide is a
bimolecular nucleophilic substitution (SN2) reaction in which
triphenylphosphine is the nucleophile and the alkyl halide is
theelectrophile. Is triphenylphosphine acting like a Lewis acid,
Lewis base, Bronsted-Lowry acid, orBronsted-Lowry base? How would
you characterize the behavior of the alkyl halide?
d. In the lab, you will make your ylide by reacting
benzyltriphenylphosphonium bromide with sodium hydroxide. How would
you characterize this reaction?
e. Is the ylide that you form...
Alcohol undergo substitution to form alkyl halides. HBr, SOCL2, and PBr3 are reagents used in these reactions. Which reagent would you use in each reaction? Give reasons.
Decide the mechanism by which the following alkyl halides will be converted to alcohols by the substitution of the nucleophile, OH-. R-X + OH- → R-OH + X- SN1 SN2 more information needed 2-chloro-2-methylpropane SN1 SN2 more information needed 1-bromobutane SN1 SN2 more information needed 2-chloro-3-methylbutane SN1 SN2 more information needed 3-chloro-3-ethylpentane