Question

Which of the following alcohols would undergo Sn2 substitution to an alkyl halide (using HBr) the...

Which of the following alcohols would undergo Sn2 substitution to an alkyl halide (using HBr) the fastest? Explain.

CH3CH2CH(OH)CH3b. CH3CH2CH2OHc. (CH3)3COH

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Answer #1

answer is

b. CH3CH2CH2OH

because sterically free as compared to seconadr and tertiary alcohol.due to stericlly free ,the nucleophile can easily attacks from back side while leavig the OH^-1 from front side. that is posible only in primary alcohol.

so b .CH3CH2CH2OH is a primary alcohol so is very fast react towards SN^2 REACTION.

3 HC-Hoc .3 H OH tけ,天

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