Question

1. The C-terminal amino acid of the hexapeptide, Asp-Ala-ser-Glu-Val-Arg is;

2. Which of the following would be observed in a person after one week of starvation?

	A.	The brain uses glucose and ketone bodies
	B.	Liver glycogen stores are only partially depleted due to an increase in gluconeogenesis
	C.	Fatty acids from adipose stores are the major source of energy for red blood cells
	D.	Muscle glycogen stores are used to maintain glucose
	E.	Nitrogen balance is maintained because muscle protein releases amino acids to compensate for lack of dietary protein

Answer 1

Answer :

1) Arginine (Arg)

• As we know mRNA is translated into protein sequences.
• Their is a convention of writing protein sequences i.e. from N to C terminal.
• N- terminal is the left end and C- terminal is the right end of protein sequences.
• We can say that N-terminal is the starting and the C-terminal is the end of protein sequence.
• Hence,C-terminal of above hexapeptide is Arg i.e.Arginine.

2) (A) Brain uses ketone and glucose for source of energy.

Explanation :

• Liver glycogen stores are fully used inspite of increasing gluconeogenesis.
• Blood glucose level are maintained through production of glucose from protein,glycogen and fats.Hence fats are not the major source of energy for red blood cells.
• Muscle's protein stores are used to maintain glucose.
• Nitrogen balance is not maintained during starvation.

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