Question

11. In glycolysis, the hydrolysis of phosphoenol pyruvate is thermodynamically driven by the highly exergonic enol-to-keto conversion of pyruvate. From the two half reactions shown below, what is the AGo of the complete reaction? (5 pts) Half Reactions COO C00 C-O-PO," + H2O C-O-H + HPO, AGʻ=-16 kJ. mol-! н н н н COO COO C=0 H-C-H ċ-0-H AGO = 45.9 kJ. mol- HH Complete Reaction COO ÇOO C-O-PO," + H2O C=O + HPO, H-C-H с HH

Answer 1

if we reverse the second half-reaction add both the reaction we will get

Half Reactions ÇOO C-O-PO," + H2O Соо C-O-H + HPO," AG"=-16 kJ. mol-1 COO COO- T C- 0- H C= 0 AG" = - 45.9 kJ. mol-1 H- C-H HH Complete Reaction COO COO C-O-PO," + HO CEO + HPO, H-C-H

Upon reverse, the second reaction delta Go' value will also be reversed.

Upon adding both values we will get -16kJ.mol-1 + ( -45.9.kJ*mol-1)

= -61.9kJ*mol-1

So deltaGo for complete reaction will be -61.9kJ*mol-1.

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