1. Predict the product of the following reactions. D is deuterium, an isotope of hydrogen with...
how would you synthesize the following
Deuterium (D)) is an isotope of hydrogen (H). Both D and H have one proton and one electron; H has no neutrons and D has one. Consequently, D and H have nearly identical behavior. but they can be distinguished from each other experimentally due to their different masses. Therefore, replacing an H with a D in a molecule - deuterium isotope labeling-can provide valuable information about a mechanism. With this in mind, how would...
(16) 6. Deuterium is the isotope of hydrogen of mass number 2, with a proton and a neutron in its nucleus. It is often designated 2H, or D. We have seen that the chemistry of deuterium is nearly identical to the chemistry of hydrogen, except that the C-D bond is slightly (1.2 kcal/mole) stronger than the C-H bond. a) Propose (show) a mechanism to explain each product in the following reaction: CH2-CHCH CH CH CH3 CH3 CH CH3 KOH +...
Mun CHEM 2252 Problem Set #2 Vaug 1. Predict the product(s) of the following reactions. Include stereochemistry in your answer whe relevant Actcl twatcr 1.H2SO4, HgSO4, H20 2. CH3MgBr O-1 H-O-H Ht2D 3. H+ Hz0 .C-H =H 1. PBr3 2. Mg 3. CH3COCH3 OH 4. H+ -cH3 Br Ma13r 1. Predict the product(s) of the following reactions. Include stereochemistry in your answer whe relevant. Acrcl twatcr 1.H2SO4, HgSO4, H20 2. CH3MgBr 3. H+ - .C-H 1 PR...
Mun CHEM 2252...
Give the major organic product(s) of the following reactions or
sequences of reactions. Show the stereochemistry and/or isotope
position clearly where it is relevant. If you think that the
reaction would not occur, write as "NR" or "No Reaction."
NaOH ? *O*CH3 H2O Note: ΑΙ H DIBAH 1) DIBAH 2) H20 C.
1. Predict the product(s) for each of the following reactions: H2SO4 NH2 a. 0 1. H2N-NH2, H2S04, -H20 H 2. KOH/H2O b. MeOH, TsOH он H2O C. H2SO4, -H20 HO d. H2O, H30+ e. H20,H30+ 2. Predict the product and draw the full pushing arrow mechanism for the following reaction NH2 H20,H30+ a. b. 3. Devise an efficient synthesis for the following transformation. HO Br Br
1) Predict the outcome of the following 4 reactions
1) Predict the outcome of the following 4 reactions MeOH Ph reflux XPh MeΝΟ, reflux Y Br MeNO2 MeSNa DMSO Ph reflux Br 2) For the following 5 molecules predict whether an E2 elimination would be possible for the DRAWN conformation. Do not attempt to rotate around any bonds, judge based on the conformation shown. If yes, show the product. Br Ph BCH Meph Me Y y o tadi men 3)...
3. Predict the majoe product(s) for the following reactions. Show the stereochemistry of the product(s) when applicable. HCI (1) Hg(OAc)2 (2) NaBH4 (1) BH3 THF (2) H202. OH Br, Br2. H20 Pt (I) CH3CO3H (2) H,O+ (2) DMS HBr ROOR
ve the major organic product(s) for each of the following reactions or sequences of reactions relevant stercochemistry. ng reactions or sequences of reactions. Show all Ph 1. NaOH, H20; H+ NHMe 2. SOCI2 3. MeOH, pyridine ethanol, pyridine 1. H30* Ph-CN 2. MeOH, H+ PhoH 1. SOCI 2. 2-butanol HO Ph Ph OH 1. SOCI 2. diethylamine I:NH CH A4
3. For each of the reactions shown below, predict the single major product and determine which mechanism, S1, Sh2, E1, or E2, is operative. Briefly justify your choice. Be sure to indicate stereochemistry in the product if it is relevant s Ko'Bu BUOH C. conc. H2SO4 d. [1 equiv ) NaOMe Br MeOH
3. Predict the major product(s) for the following reactions. Show the stereochemistry of the product(s) when applicable. (a) (e) Br2, H20 H2 PL (1) Os04 (2) NaHSO4, H20 (1) 03 (2) DMS (1) CH2CO3H (2) H30*