Please fill in the blanks!Homework Answers
PART -A
Ans- Asp149 then Glu117 then Tyr409
PART -B
Ans- GAC then GABC then Covalent catalyst and GABC then Decrease then Increase
PART -C
Ans- Sp3 then Sp2 then Increase then Sp2 to Sp3
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Shown below is a proposed mechanism for the cleavage of sialic...
Shown below is a proposed mechanism for the cleavage of sialic acid by the viral enzyme neuramini...
Shown below is a proposed mechanism for the cleavage of sialic acid by the viral enzyme neuraminidase. The kat for the wild-type enzyme at pH- 6.15, 37 Cis 26.8s-1 0 D149 OH OH 1st Step ROH R374 E117 117) +H2O ↓ 2nd Step Y409 0149 D149) OH OH OH R374 0 17) (E117) Part A Match the items in the left column to the appropriate bianks in the sestence on the right [Reset] [H삔 Glu117 Tyr4os Asp149 ads as a...
2) (14 pts) Shown on the next page is a schematic drawing of the mechanism for...
2) (14 pts) Shown on the next page is a schematic drawing of the mechanism for an RNase. Residues that are important for catalysis are also shown schematically. (a) Refer to the scheme and describe the roles of His 12, Lys 41, and His 119 in the catalytic mechanism. List all of the following that apply: general acid/base catalysis (GABC), covalent catalysis, electrostatic stabilization of transition state. For a GABC, indicate in which step(s) of the mechanism the residue acts...
ch 14 answer each of these. answer all 3 please HI HCI reactants Reaction intermediates are...
ch 14 answer each of these.
answer all 3 please
HI HCI reactants Reaction intermediates are species that are formed in one step of a mechanism and consumed in another step. For example, can act as an intermediate in the following reaction: H2(g) + 2Cl(g) + 2HCl(g) + 12(g). You can often express the concentration of in terms of the concentrations of the of the overall reaction to be consistent with the experimentally observed rate law as the overall reaction...
biochemistry if you could please help me answer the following questions! * 1. (5 pts) Which...
biochemistry
if you could please help me answer the following questions!
* 1. (5 pts) Which of the following is a catalytic mechanism utilize by enzymes? Multiple answers may be correct. Select all that are correct. 1. Acid-base a) acid-base catalysis d. metal-ion catalysis 12. Covalent b covalent catalysis e. transition state binding c. heterogeneou 3. Metalion . Proximin onentation, E 2. 76 pts) What is the "steady-state" assumption in the derivation of the s.clectrosch? Tynsin Michaelis-Menten equation? Sie binding...
kcal/K 210 Which mutation below is the least detrimental to the enzyme function? PH 8.0 variant...
kcal/K 210 Which mutation below is the least detrimental to the enzyme function? PH 8.0 variant keat (min-) Km (M) wild-type 3200 HS7A 0.054 H57L 0.075 HS7D 0.78 HSTE 0.69 HSOK 0.83 HSOR 0.017 DIO2N 1.3 H57A, D102N 0.17 H57D, D102N 0.18 H57K, D102N 0.41 H57L, D102N 0.13 S195A 0.079 S19ST 0.011 H57A, D102N, S195A 0.038 kbuffer (min) no enzyme 6.0 x 10-7 21 4.2 87 62 0.0032 0.0037 0.06 0.033 0.020 0.00025 0.30 0.0019 0.0029 0.023 0.0031 0.0019 0.00052...
Based on the document below, 1. Describe the hypothesis Chaudhuri et al ids attempting to evaluate;...
Based on the document below,
1. Describe the hypothesis Chaudhuri et al ids attempting to
evaluate; in other words, what is the goal of this paper? Why is he
writing it?
2. Does the data presented in the paper support the hypothesis
stated in the introduction? Explain.
3.According to Chaudhuri, what is the potential role of thew
alkaline phosphatase in the cleanup of industrial waste.
CHAUDHURI et al: KINETIC BEHAVIOUR OF CALF INTESTINAL ALP WITH PNPP 8.5, 9, 9.5, 10,...
Shown below is a proposed mechanism for the cleavage of sialic acid by the viral enzyme neuraminidase. The kat for the wild-type enzyme at pH- 6.15, 37 Cis 26.8s-1 0 D149 OH OH 1st Step ROH R374 E117 117) +H2O ↓ 2nd Step Y409 0149 D149) OH OH OH R374 0 17) (E117) Part A Match the items in the left column to the appropriate bianks in the sestence on the right [Reset] [H삔 Glu117 Tyr4os Asp149 ads as a...
2) (14 pts) Shown on the next page is a schematic drawing of the mechanism for an RNase. Residues that are important for catalysis are also shown schematically. (a) Refer to the scheme and describe the roles of His 12, Lys 41, and His 119 in the catalytic mechanism. List all of the following that apply: general acid/base catalysis (GABC), covalent catalysis, electrostatic stabilization of transition state. For a GABC, indicate in which step(s) of the mechanism the residue acts...
ch 14 answer each of these.
answer all 3 please
HI HCI reactants Reaction intermediates are species that are formed in one step of a mechanism and consumed in another step. For example, can act as an intermediate in the following reaction: H2(g) + 2Cl(g) + 2HCl(g) + 12(g). You can often express the concentration of in terms of the concentrations of the of the overall reaction to be consistent with the experimentally observed rate law as the overall reaction...
biochemistry
if you could please help me answer the following questions!
* 1. (5 pts) Which of the following is a catalytic mechanism utilize by enzymes? Multiple answers may be correct. Select all that are correct. 1. Acid-base a) acid-base catalysis d. metal-ion catalysis 12. Covalent b covalent catalysis e. transition state binding c. heterogeneou 3. Metalion . Proximin onentation, E 2. 76 pts) What is the "steady-state" assumption in the derivation of the s.clectrosch? Tynsin Michaelis-Menten equation? Sie binding...
kcal/K 210 Which mutation below is the least detrimental to the enzyme function? PH 8.0 variant keat (min-) Km (M) wild-type 3200 HS7A 0.054 H57L 0.075 HS7D 0.78 HSTE 0.69 HSOK 0.83 HSOR 0.017 DIO2N 1.3 H57A, D102N 0.17 H57D, D102N 0.18 H57K, D102N 0.41 H57L, D102N 0.13 S195A 0.079 S19ST 0.011 H57A, D102N, S195A 0.038 kbuffer (min) no enzyme 6.0 x 10-7 21 4.2 87 62 0.0032 0.0037 0.06 0.033 0.020 0.00025 0.30 0.0019 0.0029 0.023 0.0031 0.0019 0.00052...
Based on the document below,
1. Describe the hypothesis Chaudhuri et al ids attempting to
evaluate; in other words, what is the goal of this paper? Why is he
writing it?
2. Does the data presented in the paper support the hypothesis
stated in the introduction? Explain.
3.According to Chaudhuri, what is the potential role of thew
alkaline phosphatase in the cleanup of industrial waste.
CHAUDHURI et al: KINETIC BEHAVIOUR OF CALF INTESTINAL ALP WITH PNPP 8.5, 9, 9.5, 10,...
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