Question

A manufacturer of a margarine spread containing phytosterols claims that a person’s cholesterol can be lowered by 10% using this product for 3 months. Does the use of this margarine (with 2g of phytosterols to a 500g tub) for 3 months reduce the LDL-cholesterol level in the blood of healthy adults? a) Design an experiment to answer this question. Comment on elements of control, randomisation and replication in your design. Your answer should include a flow-chart schematic with full annotations. b) State what type of data summary statistics you would measure in your planned study. c) State what type of inferential analysis you would apply to make a decision about the manufacturer’s claim. (No actual analysis is done ... no data given.).

Answer 1

We first select a homogenous sample of adults.then we note the cholestorol level of their blood.we then condition them on same dose of drugs.after 3 months we again note down the cholesterol level.we define a random variable x that denotes the reduction in cholestorol level.we use the summary statistic sample mean of X .then we would test the null hypothesis that there is no change in cholesterol level.then we would assign a level of significance.then we note the p value.if p value is less than level of significance then we reject null hypothesis.else we fail to reject null hypothesis