Draw an appropriate alkyl halide and a nucleophile in conjugate base form that are required to give cis-4-Isopropylcyclohexanol.
Draw an appropriate alkyl halide and a nucleophile in conjugate base form that are required to...
Problem 6.26f Draw an appropriate alkyl halide and a nucleophile in conjugate base form that are required to give the following compound: Problem 6.26f Draw an appropriate alkyl halide and a nucleophile in conjugate base form that are required to give the following compound: Alkyl halide reactant: 2 Edit Nucleophile reactant: Edit
y) Predict the products of the following alkyl halide reactions. (Hint: are the alkyl halides 1,2, or type of nucleophile or base are we using?) (11 pts) wide NaOCH-CH3 CH,CH,OH cl" Η OH сн. кон
Draw the structure of the alkyl bromide and the nucleophile that will react in an SN2 reaction to give the product shown CH3 H3C CH3 Alkyl bromide + Nucleophile> CH3
predict the major organic product formed in the following reaction alkyl halide nucleophile CH, e) H Br KOBu" HOBu Br Н CH Br CH,CH,OH two products formed 8 + CHI h) Br NaOCH H
strong nucleophile weak base strong bulky base strong nucleophile strong base Promote SN2/E2 weak nucleophile weak base Promote SN1/E1 Promote SN2 Promote E2 CH Br HS NCT HO CHO CHÚCHO NaNO NaOH NOME Noe HOORS Conjugate acids have pka 16-18 Conjugate acids Recall, you make hydroxide have pka 11 or alkoxide ons from the corresponding alcohol or water and Nat CH,OH (MOH) HO CH,CH,OH (EXOH) | HC-Ć-o to CH tert-BUOK NOCH KOHBU NEOBU The structures above are all ways of...
Q.1. Draw the conjugate base or conjugate acid of the following species Conjugate Acid Conjugate Base a) OH Sb) ? CH3NH2 c) HO d) ? SO- Q.2. ) Circle the most acidic proton and cross out the least acidic protons among the shown hydrogen atoms in the following molecules. NO H NH2 O-H Η Η CH3 OH -SC-H Н" Q.3. Circle the most acidic compound and cross out the least acidic compound in each set. ou la olagla ОН OH...
(12 points) Esters can be prepared by nucleophilic substitution of an alkyl halide or via acyl substitution reactions. Show the compounds required to synthesize the ester two different ways. Be sure the product will be favored. 4. H0 alkyl halide nucleophile acyl derivative nucleophile Given the information in the question above, provide appropriate reactants above. hat does a nucleophilic substitution reaction look like in general? Acyl substitution? (12 points) Esters can be prepared by nucleophilic substitution of an alkyl halide...
Draw the structure of the alkyl bromide and the nucleophile that will react in an SN2 reaction to give the product shown. Alkyl bromide + Nucleophile C CH You do not have to consider stereochemistry. Separate multiple reactants using the + sign from the drop-down menu. . * C P opy c ▼ 田▼ /.メノ//. O O ▼ []±
Draw the structure of the alkyl bromide and the nucleophile that will react in an SN2 reaction to give the product shown. Draw the structure of the alkyl bromide and the nucleophile that will react in an SN2 reaction to give the product shown. 2 CN Alkyl bromide Nucleophile H3C You do not have to consider stereochemistry. Separate multiple reactants using the sign from the drop-down menu. C P ChemDoodle Chem Doodle
Substitution Problems I. In each of the problems below, label the alkyl halide as primary, secondary, or tertiary, Label the nucleophile as strong or weak. Decide whether an S2 or an Sol reaction occurs. Alter, show the mechanism and product or products. Indicate stereochemistry where appropriate. a. Reaction of 1-bromopropane and sodium methoxide in methanol + Na CH₂ CH OH b. Reaction of 2-bromopropane in ethanol Br + CH.CH, OH - c. Reaction of (R) 3-chloro-3-methylheptane in acetic acid CH3...