Question

Toofs 34. Which of the following is a kinase involved in the recognition and removal of misfo lded proteins A) ATF6 B) Bip C) PERK D) A and B E) All of the above 35. A GPI anchored protein will finally reside where A) In the Golgi B) In the ElR C) In the plasma membrane facing the cytosol D) In the plasma membrane facing the extracellular environment E) In the lysosome 36. Manmose-6-phosphate (M6P) is the single to be delivered to which of the following A) Golgi B) ER

Answer 1

34.

Option C is correct.

PERK is a protein involved in the physical controlling process of ER and mitochondria.

Protein kinase R like endoplasmic reticulum like kinase are stress transducer and they recognise misfolded and damaged proteins and then remove them. They are involved in the autophagy and phagocytosis.

ATF 6 is a protein activation of transcription factor. They are involved in the transcription activation process.

Bip a src kinase and involved in various signalling process but not in the removal of proteins.

35.

Glycosylphosphatidylinositol is a glycolipid and present at the c - Terminus of protein attached by the post translational modification.

These are cell surface proteins and present in the cell membrane facing extracellular side of the cell membrane.